HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: CHM2B (Q9UQN3)
Charged multivesicular body protein 2b (CHMP2.5) (Chromatin-modifying protein 2b) (CHMP2b) (Vacuolar protein sorting-associated protein 2-2) (Vps2-2) (hVps2-2)
Gene: CHMP2B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	39079530
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0019904 - protein domain specific binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 213
+	Hs
		221837 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		CHM2A_HUMAN (3-188): 1.88e-37: 131: 32.80
+	Hs
		791744 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		CHM1A_HUMAN (14-210): 2.02e-30: 112: 17.26
+	Hs
		791488 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		CHM1B_HUMAN (14-210): 5.03e-29: 109: 18.27
+	Hs
		791725 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		CHM4B_HUMAN (8-200): 6.08e-23: 94: 21.89