HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: CHM1A (Q9HD42)
Charged multivesicular body protein 1a (Chromatin-modifying protein 1a) (CHMP1a) (Vacuolar protein sorting-associated protein 46-1) (Vps46-1) (hVps46-1)
Gene: CHMP1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008270 - zinc ion binding GO:0019904 - protein domain specific binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 196
+	Hs
		791848 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		CHM2B_HUMAN (1-194): 4.61e-39: 134: 17.26
+	Hs
		221837 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		CHM2A_HUMAN (1-177): 6.6e-38: 132: 24.29
+	Hs
		791488 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		CHM1B_HUMAN (1-196): 1.75e-35: 125: 55.61
+	Hs
		791725 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		CHM4B_HUMAN (2-191): 1.51e-15: 73.6: 17.68