HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: TLN2 (Q9Y4G6)
Talin-2
Gene: TLN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36634849
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0015629 - actin cytoskeleton
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 2542
+	Hs
		791858 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		E41L3_HUMAN (80-1053): 1.64e-95: 338: 12.55
+	Hs
		791730 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		E41L1_HUMAN (36-531): 7.74e-93: 325: 15.62
+	Hs
		791741 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		E41L5_HUMAN (52-754): 7.43e-82: 289: 15.52
+	Hs
		582695 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		EZRI_HUMAN (86-670): 2.78e-80: 279: 14.82
+	Hs
		767394 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		RADI_HUMAN (175-407): 2e-44: 174: 21.72
+	Hs
		791843 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		MACF1_HUMAN (462-2538): 1.95e-33: 145: 10.74
+	Hs
		791313 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		DYST_HUMAN (785-2538): 1.26e-12: 76.3: 11.02