HitPredict

Interactor 1: MUC18 (P43121)
Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146)
Gene: MCAM

Interactor 2: PTN13 (Q12923)
Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1)
Gene: PTPN13

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38117590
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 646 Hs			1 2485
+	Hs
		505577 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		EPB41_HUMAN (414-1119): 2.11e-118: 400: 16.97
+	Hs
		793472 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		E41L1_HUMAN (471-1098): 1e-116: 395: 18.37
+	Hs
		204628 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		E41L2_HUMAN (367-1065): 2.11e-113: 389: 17.33
+	Hs
		793291 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		PTPRJ_HUMAN (1183-2475): 1.09e-110: 389: 14.37
+	Hs
		719405 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		MERL_HUMAN (558-1049): 1.41e-117: 388: 23.65
+	Hs
		793480 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		E41L5_HUMAN (513-1220): 6.79e-115: 385: 16.35
+	Hs
		719677 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RADI_HUMAN (574-969): 6.68e-116: 383: 26.94
+	Hs
		793298 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		PTPRS_HUMAN (1007-2468): 3.28e-92: 337: 12.77
+	Hs
		576997 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		PTPRA_HUMAN (2194-2468): 1.65e-96: 334: 31.10
+	Hs
		489921 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		PTPRF_HUMAN (2189-2468): 4.55e-89: 326: 30.38
+	Hs
		793325 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		PTN14_HUMAN (553-1426): 3.67e-75: 277: 15.87
+	Hs
		719746 KIRR3_HUMAN (6-625): 1.84e-82: 278: 18.22		RADI_HUMAN (574-969): 6.68e-116: 383: 26.94
+	Hs
		660833 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		PTPRM_HUMAN (2186-2471): 5.6e-58: 224: 24.92
+	Hs
		985950 PTK7_HUMAN (17-627): 1.64e-70: 249: 12.68		PTN11_HUMAN (2083-2480): 4.2e-117: 387: 31.47
+	Hs
		793317 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		PTPRK_HUMAN (2206-2470): 8.98e-55: 214: 23.83
+	Hs
		617087 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		PTPRG_HUMAN (2228-2472): 1.03e-46: 187: 25.87
+	Gg
		47583 CNTN1_CHICK (16-618): 6.28e-65: 233: 12.99		A0A8V0YWD3_CHICK (2196-2468): 1e-94: 331: 31.32
+	Hs
		640221 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		PTN3_HUMAN (1207-1558): 1.58e-17: 91.9: 11.02
+	Hs
		1069952 PXDN_HUMAN (183-555): 5.6e-61: 222: 20.77		PTPRK_HUMAN (2206-2470): 8.98e-55: 214: 23.83
+	Hs
		665883 PTK7_HUMAN (17-627): 1.64e-70: 249: 12.68		PTN6_HUMAN (2215-2480): 9.54e-47: 181: 40.48