HitPredict

Interactor 1: MUC18 (P43121)
Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146)
Gene: MCAM

Interactor 2: KS6A2 (Q15349)
Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)
Gene: RPS6KA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31678930
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~V-set
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 733
+	Hs
		793321 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		KS6A1_HUMAN (25-733): 0: 797: 80.11
+	Hs
		270448 ROBO2_HUMAN (1-646): 1.16e-96: 325: 14.69		KS6A5_HUMAN (38-727): 0: 712: 41.00
+	Hs
		1071679 KIRR1_HUMAN (240-644): 1.88e-28: 123: 15.77		KS6A2_HUMAN (1-733): 0: 824: 100.00
+	Hs
		530144 NCAM1_HUMAN (11-644): 1.38e-81: 277: 15.63		KAPCA_HUMAN (402-707): 8.01e-119: 362: 29.78