HitPredict

Interactor 1: MSH2 (P43246)
DNA mismatch repair protein Msh2 (hMSH2) (MutS protein homolog 2)
Gene: MSH2

Interactor 2: H33 (P84243)
Histone H3.3
Gene: H3-3A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36089195
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008584 - male gonad development
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 934 Hs			1 136
+	Hs
		794232 MSH2_HUMAN (1-934): 0: 1120: 100.00		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Sc
		639281 MSH2_YEAST (10-931): 0: 806: 39.53		H3_YEAST (1-136): 3.62e-54: 168: 90.44
+	Hs
		855452 MSH6_HUMAN (7-855): 0: 787: 22.11		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		855454 MSH6_HUMAN (7-855): 0: 787: 22.11		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Hs
		111558 MSH6_HUMAN (7-855): 0: 787: 22.11		K7EK07_HUMAN (1-132): 7.81e-58: 177: 100.00
+	Hs
		828177 MSH6_HUMAN (7-855): 0: 787: 22.11		CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76
+	Hs
		594184 MSH3_HUMAN (6-861): 0: 721: 23.13		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		594185 MSH3_HUMAN (6-861): 0: 721: 23.13		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Sc
		902039 MSH6_YEAST (7-862): 0: 702: 22.62		H3_YEAST (1-136): 3.62e-54: 168: 90.44
+	Hs
		594175 MSH3_HUMAN (6-861): 0: 721: 23.13		CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76