Protein: CHD1
Chromo domain-containing protein 1 (EC 3.6.4.-) (ATP-dependent helicase CHD1)

Gene: CHD1
Organism: Saccharomyces cerevisiae S288C
Interactions: 157
UniProt ID: P32657

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0000182 - rDNA binding
GO:0000724 - double-strand break repair via homologous recombination
GO:0000729 - DNA double-strand break processing
GO:0000785 - chromatin

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

381974

H4
Histone H4

9

12

Small-scale

0.970

High

744327

H3
Histone H3

6

20

Small-scale

0.933

High

744289

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

4

17

Small-scale

0.892

High

381029

H2B1
Histone H2B.1

3

20

Small-scale

0.827

High

744355

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

2

17

High-throughput

0.802

High

744337

RUVB1
RuvB-like protein 1

2

6

High-throughput

0.789

High

744341

POB3
FACT complex subunit POB3

9

8

Small-scale

0.750

High

585889

CSK21
Casein kinase II subunit alpha

7

10

Small-scale

0.749

High

622904

CSK22
Casein kinase II subunit alpha'

7

13

Small-scale

0.749

High

739573

SPT16
FACT complex subunit SPT16

8

4

Small-scale

0.749

High

419664

H2A2
Histone H2A.2

2

20

High-throughput

0.737

High

744367

H2AZ
Histone H2A.Z

2

20

High-throughput

0.737

High

647062

RPC2
DNA-directed RNA polymerase III subunit RPC2

2

0

High-throughput

0.720

High

744269

CHD1
Chromo domain-containing protein 1

1

17

High-throughput

0.665

High

744298

CSK2C
Casein kinase II subunit beta'

5

4

Small-scale

0.657

High

744314

CSK2B
Casein kinase II subunit beta

5

4

Small-scale

0.657

High

744322

RTF1
RNA polymerase-associated protein RTF1

3

0

Small-scale

0.648

High

419391

H2A1
Histone H2A.1

1

20

Small-scale

0.647

High

744307

ATAD2
ATPase histone chaperone YTA7

3

5

High-throughput

0.633

High

638988

VPS1
Vacuolar protein sorting-associated protein 1

2

1

High-throughput

0.621

High

744366

CMR1
DNA damage-binding protein CMR1

1

14

High-throughput

0.621

High

381459

H2B2
Histone H2B.2

1

20

High-throughput

0.618

High

594272

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.618

High

734401

BTAF1
TATA-binding protein-associated factor MOT1

1

16

Small-scale

0.618

High

743066

STH1
Nuclear protein STH1/NPS1

1

16

High-throughput

0.618

High

744274

NCBP1
Nuclear cap-binding protein complex subunit 1

1

1

High-throughput

0.618

High

744281

CENPA
Histone H3-like centromeric protein CSE4

1

20

High-throughput

0.618

High

744288

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

12

Small-scale

0.618

High

744345

ARP9
Actin-like protein ARP9

1

17

High-throughput

0.618

High

744364

ARP7
Actin-related protein 7

1

12

High-throughput

0.618

High

744348

PDP3
NuA3 HAT complex component PDP3

2

9

Small-scale

0.611

High

744359

SCC1
Sister chromatid cohesion protein 1

2

4

Small-scale

0.611

High

544238

SSB1
Ribosome-associated molecular chaperone SSB1

2

11

High-throughput

0.601

High

744311

DSN1
Kinetochore-associated protein DSN1

2

1

High-throughput

0.584

High

744342

RCO1
Transcriptional regulatory protein RCO1

1

20

High-throughput

0.575

High

744346

SWR1
Helicase SWR1

1

18

High-throughput

0.575

High

744333

HOS3
Histone deacetylase HOS3

2

20

High-throughput

0.571

High

744335

GCN5
Histone acetyltransferase GCN5

2

20

Small-scale

0.571

High

670498

SIS1
Protein SIS1

1

1

High-throughput

0.536

High

744369

HSH49
Protein HSH49

1

7

High-throughput

0.536

High

569945

RL3
Large ribosomal subunit protein uL3

2

2

High-throughput

0.521

High

744272

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

3

High-throughput

0.515

High

744297

HRB1
Serine/arginine

1

10

High-throughput

0.515

High

744332

ABF2
ARS-binding factor 2, mitochondrial

1

20

High-throughput

0.515

High

744290

CND2
Condensin complex subunit 2

1

0

Small-scale

0.513

High

517959

SSBP1
Single-stranded nucleic acid-binding protein

1

16

High-throughput

0.501

High

744292

PAF1
RNA polymerase II-associated protein 1

1

3

Small-scale

0.501

High

744293

LEO1
RNA polymerase-associated protein LEO1

1

4

Small-scale

0.501

High

744328

CTR9
RNA polymerase-associated protein CTR9

1

11

Small-scale

0.501

High

744349

CDC73
Cell division control protein 73

1

2

Small-scale

0.501

High

744287

BOI1
BEM1-interacting protein 1

1

7

High-throughput

0.494

High

434948

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

448942

TOP2
DNA topoisomerase 2

1

8

High-throughput

0.479

High

678307

RSC6
Chromatin structure-remodeling complex protein RSC6

1

10

High-throughput

0.479

High

679509

CDC48
Cell division control protein 48

1

2

High-throughput

0.479

High

684661

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.479

High

694506

SPT5
Transcription elongation factor SPT5

1

7

Small-scale

0.479

High

706572

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

734900

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

744271

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

6

High-throughput

0.479

High

744275

SAS3
Histone acetyltransferase SAS3

1

6

High-throughput

0.479

High

744276

SPT7
SAGA complex subunit SPT7

1

20

Small-scale

0.479

High

744277

RRP1
Ribosomal RNA-processing protein 1

1

6

High-throughput

0.479

High

744278

SPT10
Protein SPT10

1

1

High-throughput

0.479

High

744280

BDF1
Bromodomain-containing factor 1

1

20

High-throughput

0.479

High

744294

RFC1
Replication factor C subunit 1

1

6

High-throughput

0.479

High

744296

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

1

8

Small-scale

0.479

High

744299

UME6
Transcriptional regulatory protein UME6

1

1

High-throughput

0.479

High

744304

SCC4
MAU2 chromatid cohesion factor homolog

1

1

Small-scale

0.479

High

744310

ULP2
Ubiquitin-like-specific protease 2

1

2

High-throughput

0.479

High

744313

RSC8
Chromatin structure-remodeling complex protein RSC8

1

15

High-throughput

0.479

High

744319

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

11

Small-scale

0.479

High

744321

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

2

Small-scale

0.479

High

744326

APJ1
J domain-containing protein APJ1

1

3

High-throughput

0.479

High

744329

NOP3
Serine/arginine

1

20

Small-scale

0.479

High

744331

ADA2
SAGA complex subunit ADA2

1

14

Small-scale

0.479

High

744336

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

5

Small-scale

0.479

High

744338

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

744340

PDS5
Sister chromatid cohesion protein PDS5

1

1

High-throughput

0.479

High

744344

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

3

Small-scale

0.479

High

744347

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

744350

BDF2
Bromodomain-containing factor 2

1

20

High-throughput

0.479

High

744356

TAF10
SAGA complex/transcription factor TFIID complex subunit TAF10

1

1

Small-scale

0.479

High

744360

YRA1
RNA annealing protein YRA1

1

11

High-throughput

0.479

High

744361

RIO1
Serine/threonine-protein kinase RIO1

1

3

High-throughput

0.479

High

744362

NTO1
NuA3 HAT complex component NTO1

1

14

High-throughput

0.479

High

744368

RL11B
Large ribosomal subunit protein uL5B

1

4

High-throughput

0.479

High

585237

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

5

High-throughput

0.470

High

744343

RRP5
rRNA biogenesis protein RRP5

1

8

High-throughput

0.470

High

449447

SPT3
SAGA complex subunit SPT3

1

0

Small-scale

0.458

High

657066

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.458

High

676620

SGF29
SAGA complex subunit SGF29

1

0

Small-scale

0.458

High

738139

NGG1
SAGA complex subunit NGG1

1

0

Small-scale

0.458

High

743614

RTG2
Retrograde regulation protein 2

1

0

Small-scale

0.458

High

744270

RSC7
Chromatin structure-remodeling complex subunit RSC7

1

0

High-throughput

0.458

High

744279

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

744291

LDB7
Chromatin structure-remodeling complex protein RSC14

1

0

High-throughput

0.458

High

744302

EXO1
Exodeoxyribonuclease 1

1

0

High-throughput

0.458

High

744308

MAM33
Mitochondrial acidic protein MAM33

1

0

High-throughput

0.458

High

744320

SPT20
SAGA complex subunit SPT20

1

0

Small-scale

0.458

High

744324

RT102
Regulator of Ty1 transposition protein 102

1

0

High-throughput

0.458

High

744334

RSC9
Chromatin structure-remodeling complex subunit RSC9

1

0

High-throughput

0.458

High

744339

IOC4
ISWI one complex protein 4

1

0

High-throughput

0.458

High

744353

SGO1
Shugoshin

1

0

High-throughput

0.458

High

744357

HFI1
SAGA complex subunit HFI1

1

0

Small-scale

0.458

High

744358

IOC2
ISWI one complex protein 2

1

0

High-throughput

0.458

High

744370

HTL1
High temperature lethal protein 1

1

0

High-throughput

0.458

High

392452

HSP82
ATP-dependent molecular chaperone HSP82

1

7

High-throughput

0.445

High

448156

HAP2
Transcriptional activator HAP2

1

1

High-throughput

0.445

High

481552

HSP73
Heat shock protein SSA3

1

10

High-throughput

0.445

High

523422

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.445

High

526231

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

649936

SIN3
Transcriptional regulatory protein SIN3

1

12

High-throughput

0.445

High

671511

SWI4
Regulatory protein SWI4

1

5

High-throughput

0.445

High

675840

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.445

High

736621

ASF1
Histone chaperone ASF1

1

7

High-throughput

0.445

High

741230

HSP7F
Heat shock protein homolog SSE1

1

13

High-throughput

0.445

High

744273

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.445

High

744282

LHS1
Heat shock protein 70 homolog LHS1

1

11

High-throughput

0.445

High

744285

SET3
SET domain-containing protein 3

1

12

High-throughput

0.445

High

744295

SSZ1
Ribosome-associated complex subunit SSZ1

1

9

High-throughput

0.445

High

744300

CAJ1
Protein CAJ1

1

1

High-throughput

0.445

High

744303

HSP7E
Heat shock protein SSC3, mitochondrial

1

11

High-throughput

0.445

High

744305

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

744306

RT106
Histone chaperone RTT106

1

1

High-throughput

0.445

High

744318

RL4B
Large ribosomal subunit protein uL4B

1

4

High-throughput

0.445

High

744325

JJJ1
J protein JJJ1

1

2

High-throughput

0.445

High

744330

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

20

High-throughput

0.445

High

744354

ESA1
Histone acetyltransferase ESA1

1

6

High-throughput

0.445

High

744365

CAF1A
Chromatin assembly factor 1 subunit A

1

12

High-throughput

0.445

High

432526

RL7A
Large ribosomal subunit protein uL30A

1

2

High-throughput

0.437

High

432997

RL6B
Large ribosomal subunit protein eL6B

1

3

High-throughput

0.437

High

433169

RL17A
Large ribosomal subunit protein uL22A

1

4

High-throughput

0.437

High

433535

RL26A
Large ribosomal subunit protein uL24A

1

3

High-throughput

0.437

High

434144

RL36A
Large ribosomal subunit protein eL36A

1

2

High-throughput

0.437

High

434536

RL22A
Large ribosomal subunit protein eL22A

1

2

High-throughput

0.437

High

511160

RL20B
Large ribosomal subunit protein eL20B

1

2

High-throughput

0.437

High

514251

RL12B
Large ribosomal subunit protein uL11B

1

2

High-throughput

0.437

High

515233

RL35A
Large ribosomal subunit protein uL29A

1

2

High-throughput

0.437

High

601007

RL8A
Large ribosomal subunit protein eL8A

1

5

High-throughput

0.437

High

744284

RL14A
Large ribosomal subunit protein eL14A

1

4

High-throughput

0.437

High

744301

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

744309

RL34B
Large ribosomal subunit protein eL34B

1

1

High-throughput

0.437

High

744312

RL10
Large ribosomal subunit protein uL16

1

4

High-throughput

0.437

High

744315

RL17B
Large ribosomal subunit protein uL22B

1

4

High-throughput

0.437

High

744323

RL26B
Large ribosomal subunit protein uL24B

1

3

High-throughput

0.437

High

744352

BRX1
Ribosome biogenesis protein BRX1

1

5

High-throughput

0.437

High

744351

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

671604

SCJ1
DnaJ-related protein SCJ1

1

1

High-throughput

0.407

High

744286

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.269

Low

550637

SIR4
Regulatory protein SIR4

1

0

Small-scale

0.251

Low

558649

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

744317

RL37A
Large ribosomal subunit protein eL37A

1

0

High-throughput

0.249

Low

744283

CAB3
Coenzyme A biosynthesis protein 3

1

0

High-throughput

0.238

Low

744316

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.232

Low

744363

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025