Protein: IOC2
ISWI one complex protein 2

Gene: IOC2
Organism: Saccharomyces cerevisiae S288C
Interactions: 64
UniProt ID: Q12072

Gene Ontology (top 5):
GO:0006338 - chromatin remodeling
GO:0006355 - regulation of DNA-templated transcription
GO:0009408 - response to heat
GO:0016587 - Isw1 complex
GO:0036437 - Isw1b complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

794234

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

6

1

Small-scale

0.733

High

1046011

IOC4
ISWI one complex protein 4

4

0

Small-scale

0.649

High

1084230

H2AZ
Histone H2A.Z

3

1

High-throughput

0.633

High

382406

H4
Histone H4

3

0

High-throughput

0.606

High

823057

ATAD2
ATPase histone chaperone YTA7

3

0

High-throughput

0.606

High

963781

H3
Histone H3

3

0

Small-scale

0.606

High

381304

H2B1
Histone H2B.1

2

1

High-throughput

0.571

High

850388

IOC3
ISWI one complex protein 3

2

0

High-throughput

0.551

High

1061381

RSC58
Chromatin structure-remodeling complex protein RSC58

2

0

High-throughput

0.547

High

381665

H2B2
Histone H2B.2

1

1

High-throughput

0.479

High

743152

STH1
Nuclear protein STH1/NPS1

1

2

High-throughput

0.479

High

777136

BDF1
Bromodomain-containing factor 1

1

1

High-throughput

0.479

High

678352

RSC6
Chromatin structure-remodeling complex protein RSC6

1

0

High-throughput

0.458

High

744358

CHD1
Chromo domain-containing protein 1

1

0

High-throughput

0.458

High

796042

LDB7
Chromatin structure-remodeling complex protein RSC14

1

0

High-throughput

0.458

High

850598

RSC8
Chromatin structure-remodeling complex protein RSC8

1

0

High-throughput

0.458

High

919699

RT102
Regulator of Ty1 transposition protein 102

1

0

High-throughput

0.458

High

1041009

RSC9
Chromatin structure-remodeling complex subunit RSC9

1

0

High-throughput

0.458

High

1054042

SFH1
Chromatin structure-remodeling complex subunit SFH1

1

0

High-throughput

0.458

High

1084227

ARP7
Actin-related protein 7

1

0

High-throughput

0.458

High

1084231

HTL1
High temperature lethal protein 1

1

0

High-throughput

0.458

High

1035347

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

1

High-throughput

0.445

High

734492

BTAF1
TATA-binding protein-associated factor MOT1

1

3

Small-scale

0.437

High

448239

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.426

High

694667

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.426

High

781815

SET3
SET domain-containing protein 3

1

0

High-throughput

0.426

High

546663

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.407

High

820068

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.407

High

419903

H2A2
Histone H2A.2

3

0

High-throughput

0.330

High

826919

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.305

High

1084229

CMR1
DNA damage-binding protein CMR1

2

0

High-throughput

0.305

High

744936

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

0

High-throughput

0.282

High

1084223

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.251

Low

1084225

RIO1
Serine/threonine-protein kinase RIO1

1

0

Small-scale

0.251

Low

432727

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.249

Low

449024

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.249

Low

557784

SRS2
ATP-dependent DNA helicase SRS2

1

0

High-throughput

0.249

Low

594623

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

653807

APN1
Apurinic-apyrimidinic endonuclease 1

1

0

High-throughput

0.249

Low

708476

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

710033

BMH1
Protein BMH1

1

0

High-throughput

0.249

Low

739808

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low

745912

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.249

Low

748579

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

757779

SAS3
Histone acetyltransferase SAS3

1

0

High-throughput

0.249

Low

764028

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

795261

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

801029

RFC1
Replication factor C subunit 1

1

0

High-throughput

0.249

Low

812751

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

925122

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.249

Low

1039656

NOG1
Nucleolar GTP-binding protein 1

1

0

High-throughput

0.249

Low

1039934

RT51
Small ribosomal subunit protein bS1m

1

0

High-throughput

0.249

Low

1040033

HOS3
Histone deacetylase HOS3

1

0

High-throughput

0.249

Low

1044826

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

1046535

PUF6
Pumilio homology domain family member 6

1

0

High-throughput

0.249

Low

1046954

POB3
FACT complex subunit POB3

1

0

High-throughput

0.249

Low

1064281

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

1084224

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.249

Low

1084226

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.249

Low

149233

FOB1
DNA replication fork-blocking protein FOB1

1

0

High-throughput

0.238

Low

736750

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.232

Low

811065

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.232

Low

820448

RT106
Histone chaperone RTT106

1

0

High-throughput

0.232

Low

1084228

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025