HitPredict

Interactor 1: COP1 (P43254)
E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1) (RING-type E3 ubiquitin transferase COP1)
Gene: COP1

Interactor 2: CRY2 (Q96524)
Cryptochrome-2 (Atcry2) (Blue light photoreceptor) (Protein PHR homolog 1) (AtPHH1) (Protein SUPPRESSOR OF elf3 20)
Gene: CRY2

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.670

Property	Details
Experiments	11509693, 21514160, 20624951
Identification Methods	two hybrid, affinity chromatography technology, bimolecular fluorescence complementation, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016604 - nuclear body GO:0046872 - metal ion binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 675 At			1 612
+	At
		1277618 SPA4_ARATH (42-673): 4.09e-85: 286: 31.09		CRY2_ARATH (1-612): 0: 760: 100.00
+	At
		1280993 SPA3_ARATH (449-674): 2.87e-30: 129: 19.83		CRY2_ARATH (1-612): 0: 760: 100.00
+	Hs
		1115744 FBXW7_HUMAN (185-667): 4.17e-79: 268: 13.56		CRY2_HUMAN (5-575): 0: 613: 25.13
+	At
		1280998 SPA1_ARATH (508-674): 1.28e-22: 105: 16.38		CRY2_ARATH (1-612): 0: 760: 100.00
+	At
		1280999 SPA2_ARATH (508-674): 7.65e-22: 102: 17.51		CRY2_ARATH (1-612): 0: 760: 100.00
+	At
		1115061 SPA1_ARATH (508-674): 1.28e-22: 105: 16.38		CRY1_ARATH (8-578): 0: 636: 51.97
+	At
		794474 COP1_ARATH (508-674): 7.27e-22: 102: 14.12		CRY1_ARATH (8-578): 0: 636: 51.97