HitPredict

Interactor 1: CSN8 (P43255)
COP9 signalosome complex subunit 8 (CSN complex subunit 8) (Constitutive photomorphogenesis protein 9) (Protein FUSCA 7)
Gene: CSN8

Interactor 2: CSN1 (P45432)
COP9 signalosome complex subunit 1 (CSN complex subunit 1) (Constitutive photomorphogenesis protein 11) (Protein FUSCA 6)
Gene: CSN1

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.912

Property	Details
Experiments	9878390, 8953769, 12615944, 9811788, 11701877
Identification Methods	affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation, molecular sieving
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	CSN8_PSD8_EIF3K~PCI
Common GO terms	GO:0000338 - protein deneddylation GO:0005737 - cytoplasm GO:0008180 - COP9 signalosome GO:0009585 - red, far-red light phototransduction
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 197 At			1 441
+	Mm
		102352 CSN8_MOUSE (9-197): 8.46e-84: 248: 31.88		G3UXW9_MOUSE (28-440): 4.8e-105: 323: 45.64
+	Mm
		1257402 CSN8_MOUSE (9-197): 8.46e-84: 248: 31.88		CSN1_MOUSE (28-440): 5.96e-104: 318: 45.64
+	Hs
		1024210 CSN8_HUMAN (9-197): 6.5e-86: 254: 31.40		CSN1_HUMAN (28-440): 1.81e-100: 310: 45.00
+	Hs
		897300 CSN8_HUMAN (9-197): 6.5e-86: 254: 31.40		CSN2_HUMAN (62-427): 1.2e-75: 244: 14.85
+	Mm
		897341 CSN8_MOUSE (9-197): 8.46e-84: 248: 31.88		CSN2_MOUSE (62-427): 1.2e-75: 244: 14.85