HitPredict

Interactor 1: CSN8 (P43255)
COP9 signalosome complex subunit 8 (CSN complex subunit 8) (Constitutive photomorphogenesis protein 9) (Protein FUSCA 7)
Gene: CSN8

Interactor 2: CSN5B (Q9FVU9)
COP9 signalosome complex subunit 5b (Signalosome subunit 5b) (EC 3.4.-.-) (Jun activation domain-binding homolog 2)
Gene: CSN5B

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.892

Property	Details
Experiments	9811788, 11742986, 15486099, 21798944
Identification Methods	affinity chromatography technology, two hybrid, two hybrid array
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	CSN5_C~CSN8_PSD8_EIF3K
Common GO terms	GO:0000338 - protein deneddylation GO:0005737 - cytoplasm GO:0008180 - COP9 signalosome GO:0009585 - red, far-red light phototransduction GO:0010387 - COP9 signalosome assembly
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 197 At			1 358
+	At
		794513 CSN8_ARATH (1-197): 1.45e-96: 280: 100.00		CSN5A_ARATH (1-357): 7.16e-130: 377: 85.43
+	Hs
		1272557 CSN8_HUMAN (9-197): 6.5e-86: 254: 31.40		CSN5_HUMAN (1-341): 4.52e-117: 344: 66.57
+	Mm
		193525 CSN8_MOUSE (9-197): 8.46e-84: 248: 31.88		CSN5_MOUSE (1-339): 4.47e-117: 344: 66.67
+	At
		794517 CSN8_ARATH (1-197): 1.45e-96: 280: 100.00		EIF3H_ARATH (43-350): 8.68e-73: 231: 14.73
+	An
		472979 CSN8_EMENI (42-184): 9.19e-50: 162: 22.45		CSN5_EMENI (8-347): 1.74e-108: 322: 52.63