Interactor 1: KSYK (P43405)
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)
Gene: SYK

Interactor 2: CLC7A (Q9BXN2)
C-type lectin domain family 7 member A (Beta-glucan receptor) (C-type lectin superfamily member 12) (Dendritic cell-associated C-type lectin 1) (DC-associated C-type lectin 1) (Dectin-1) (CD antigen CD369)
Gene: CLEC7A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 34362877, 31875558
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001775 - cell activation
GO:0002223 - stimulatory C-type lectin receptor signaling pathway
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0031334 - positive regulation of protein-containing complex assembly
and 11 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 635
Hs

1 247
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024