HitPredict

Interactor 1: KI2L2 (P43627)
Killer cell immunoglobulin-like receptor 2DL2 (CD158 antigen-like family member B1) (Natural killer-associated transcript 6) (NKAT-6) (p58 natural killer cell receptor clone CL-43) (p58 NK receptor CL-43) (CD antigen CD158b1)
Gene: KIR2DL2

Interactor 2: Q5QT33 (Q5QT33)
HLA class I antigen (HLA class I histocompatibility antigen C alpha chain) (HLA class I histocompatibility antigen Cw-1 alpha chain) (HLA class I histocompatibility antigen, C alpha chain) (HLA-C alpha chain) (MHC class I antigen)
Gene: HLA-C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	18322206
Identification Methods	affinity chromatography technology
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~ig, MHC_I~ig
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 348 Hs			1 366
+	Hs
		798173 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		Q5RIP0_HUMAN (1-366): 1.36e-168: 476: 96.72
+	Hs
		798171 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		Q5D1W8_HUMAN (1-366): 2.82e-167: 473: 95.90
+	Hs
		798146 KI2L1_HUMAN (1-348): 1.05e-132: 384: 94.54		Q5D1W8_HUMAN (1-366): 2.82e-167: 473: 95.90
+	Hs
		798170 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		Q53YP1_HUMAN (1-366): 4.13e-165: 467: 95.08
+	Hs
		798145 KI2L1_HUMAN (1-348): 1.05e-132: 384: 94.54		Q53YP1_HUMAN (1-366): 4.13e-165: 467: 95.08
+	Hs
		798174 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		Q7YNW6_HUMAN (1-366): 2e-163: 463: 96.45
+	Hs
		86373 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		C1K0Y5_HUMAN (1-366): 2.06e-159: 453: 96.45
+	Hs
		86372 KI2L1_HUMAN (1-348): 1.05e-132: 384: 94.54		C1K0Y5_HUMAN (1-366): 2.06e-159: 453: 96.45
+	Hs
		46937 KI2L1_HUMAN (1-348): 1.05e-132: 384: 94.54		A0A583ZBW8_HUMAN (1-366): 1.49e-158: 451: 95.36
+	Hs
		3610 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		A0A142JA41_HUMAN (1-366): 2.46e-156: 445: 97.00
+	Hs
		798175 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		Q7YQB1_HUMAN (1-366): 3.54e-155: 442: 97.00
+	Hs
		798179 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		V6DZ76_HUMAN (1-363): 3.88e-155: 442: 87.05
+	Hs
		354350 KI2L1_HUMAN (1-348): 1.05e-132: 384: 94.54		HLAB_HUMAN (1-363): 1.46e-156: 445: 87.88
+	Hs
		3609 KI2L1_HUMAN (1-348): 1.05e-132: 384: 94.54		A0A142JA41_HUMAN (1-366): 2.46e-156: 445: 97.00
+	Hs
		488155 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		HLAC_HUMAN (1-366): 5.8e-154: 439: 93.44
+	Hs
		87223 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		C9E8W1_HUMAN (1-366): 4.34e-153: 437: 90.59
+	Hs
		87838 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		D2IYK1_HUMAN (1-363): 4.64e-153: 436: 90.36
+	Hs
		46934 KI2L1_HUMAN (1-348): 1.05e-132: 384: 94.54		A0A583ZBW7_HUMAN (1-366): 3.36e-154: 439: 95.08
+	Hs
		488154 KI2L1_HUMAN (1-348): 1.05e-132: 384: 94.54		HLAC_HUMAN (1-366): 5.8e-154: 439: 93.44
+	Hs
		87222 KI2L1_HUMAN (1-348): 1.05e-132: 384: 94.54		C9E8W1_HUMAN (1-366): 4.34e-153: 437: 90.59