Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: HXK2 (P52789)
Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) (Hexokinase-B) (Muscle form hexokinase)
Gene: HK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 34591612
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0045766 - positive regulation of angiogenesis
GO:2000378 - negative regulation of reactive oxygen species metabolic process
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1863
Hs

1 917
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025