HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: NFIX (Q14938)
Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)
Gene: NFIX

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	39617063
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1863 Hs			1 502
+	Hs
		799047 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		NFIA_HUMAN (1-502): 1.45e-118: 359: 66.47
+	Hs
		473829 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		NFIC_HUMAN (3-502): 4.99e-114: 348: 53.43
+	Hs
		142874 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		NFIB_HUMAN (1-419): 3.83e-101: 311: 58.69
+	Hs
		799200 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		OBSCN_HUMAN (66-465): 4.56e-45: 172: 15.35
+	Hs
		130392 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		SPT5H_HUMAN (144-357): 1.63e-12: 72.3: 13.60
+	Hs
		323844 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		SC31A_HUMAN (196-498): 4.01e-11: 67.7: 9.78
+	Hs
		799533 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		OGFR_HUMAN (174-467): 5.45e-11: 66.9: 12.59
+	Hs
		571950 TRI27_HUMAN (13-390): 6.01e-69: 244: 11.74		NFIA_HUMAN (1-502): 1.45e-118: 359: 66.47
+	Hs
		1133628 BARD1_HUMAN (13-366): 8.77e-32: 137: 11.98		NFIX_HUMAN (1-502): 5.28e-159: 462: 100.00
+	Hs
		473761 TRI27_HUMAN (13-390): 6.01e-69: 244: 11.74		NFIC_HUMAN (3-502): 4.99e-114: 348: 53.43
+	Hs
		142810 TRI27_HUMAN (13-390): 6.01e-69: 244: 11.74		NFIB_HUMAN (1-419): 3.83e-101: 311: 58.69
+	Hs
		1087974 BARD1_HUMAN (13-366): 8.77e-32: 137: 11.98		NFIA_HUMAN (1-502): 1.45e-118: 359: 66.47
+	Hs
		474238 BARD1_HUMAN (13-366): 8.77e-32: 137: 11.98		NFIC_HUMAN (3-502): 4.99e-114: 348: 53.43
+	Hs
		143215 BARD1_HUMAN (13-366): 8.77e-32: 137: 11.98		NFIB_HUMAN (1-419): 3.83e-101: 311: 58.69
+	Hs
		572271 TRI27_HUMAN (13-390): 6.01e-69: 244: 11.74		MAGL2_HUMAN (152-497): 4.3e-09: 61.2: 8.57
+	Hs
		130595 BARD1_HUMAN (13-366): 8.77e-32: 137: 11.98		SPT5H_HUMAN (144-357): 1.63e-12: 72.3: 13.60