HitPredict

Interactor 1: VDAC2 (P45880)
Voltage-dependent anion-selective channel protein 2 (VDAC-2) (hVDAC2) (Outer mitochondrial membrane protein porin 2)
Gene: VDAC2

Interactor 2: RAB7A (P51149)
Ras-related protein Rab-7a (EC 3.6.5.2)
Gene: RAB7A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 29360040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0031966 - mitochondrial membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 207
+	Hs
		799962 VDAC2_HUMAN (1-294): 7.18e-126: 362: 100.00		RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50
+	Hs
		601201 VDAC1_HUMAN (12-294): 1.42e-110: 323: 74.56		RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50
+	Hs
		601361 VDAC1_HUMAN (12-294): 1.42e-110: 323: 74.56		RAB1B_HUMAN (1-205): 2.14e-86: 255: 34.15
+	Hs
		918970 VDAC3_HUMAN (12-294): 1.21e-108: 318: 73.50		RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50
+	Hs
		601179 VDAC1_HUMAN (12-294): 1.42e-110: 323: 74.56		RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00
+	Hs
		799949 VDAC2_HUMAN (1-294): 7.18e-126: 362: 100.00		RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44
+	Sc
		389876 VDAC1_YEAST (14-294): 5.49e-80: 245: 23.59		YPT7_YEAST (1-207): 3.66e-81: 242: 61.79
+	Hs
		330656 TOM40_HUMAN (12-290): 1.58e-72: 228: 12.63		RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50
+	Hs
		330722 TOM40_HUMAN (12-290): 1.58e-72: 228: 12.63		RAB1B_HUMAN (1-205): 2.14e-86: 255: 34.15
+	Hs
		330644 TOM40_HUMAN (12-290): 1.58e-72: 228: 12.63		RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00
+	Hs
		601178 VDAC1_HUMAN (12-294): 1.42e-110: 323: 74.56		RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44
+	Hs
		1281671 TM40L_HUMAN (1-290): 1.41e-58: 191: 15.76		RAB1B_HUMAN (1-205): 2.14e-86: 255: 34.15