HitPredict

Interactor 1: UBP5 (P45974)
Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5)
Gene: USP5

Interactor 2: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35235311
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UBA~ubiquitin, UCH~ubiquitin, ubiquitin~zf-UBP
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 858 Hs			1 156
+	Mm
		476724 UBP5_MOUSE (1-858): 0: 844: 98.37		UBC_MOUSE (1-119): 1.07e-36: 135: 67.48
+	Rn
		88803 D3ZVQ0_RAT (1-858): 0: 845: 98.25		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	Hs
		474951 UBP5_HUMAN (1-858): 0: 842: 100.00		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00
+	Mm
		476806 UBP13_MOUSE (2-858): 0: 728: 59.44		UBC_MOUSE (1-119): 1.07e-36: 135: 67.48
+	Rn
		88579 D3ZDI9_RAT (2-858): 0: 716: 59.33		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	Dm
		547964 Q9VZU7_DROME (7-855): 0: 631: 48.79		RS27A_DROME (1-156): 1.18e-72: 216: 91.03
+	At
		1091780 UBP14_ARATH (7-856): 0: 603: 46.68		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Sc
		477617 UBP14_YEAST (11-855): 4.13e-125: 397: 26.43		RL40A_YEAST (1-125): 2.07e-42: 139: 64.00
+	Hs
		924100 USP9X_HUMAN (289-758): 2.24e-84: 298: 16.20		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		924201 UBP36_HUMAN (250-817): 9.73e-85: 295: 13.61		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Sc
		408408 UBP8_YEAST (157-680): 1.03e-88: 291: 13.08		RS31_YEAST (1-151): 4.55e-61: 187: 82.78
+	Hs
		924372 USP9X_HUMAN (289-758): 2.24e-84: 298: 16.20		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Rn
		88542 D3ZC84_RAT (289-758): 9.64e-84: 296: 15.63		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	Mm
		476759 USP9X_MOUSE (289-758): 1.34e-82: 293: 15.44		UBC_MOUSE (1-119): 1.07e-36: 135: 67.48
+	Hs
		924373 UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Hs
		905374 UBP46_HUMAN (293-681): 1.18e-80: 266: 14.90		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Hs
		475123 UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00
+	Mm
		477008 UBP12_MOUSE (325-683): 1.38e-82: 271: 16.67		UBC_MOUSE (1-119): 1.07e-36: 135: 67.48
+	Mm
		476741 UBP46_MOUSE (293-681): 1.18e-80: 266: 14.90		UBC_MOUSE (1-119): 1.07e-36: 135: 67.48
+	Hs
		474982 UBP46_HUMAN (293-681): 1.18e-80: 266: 14.90		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00