Interactor 1: RAGP1 (P46060)
Ran GTPase-activating protein 1 (RanGAP1)
Gene: RANGAP1

Interactor 2: SENP1 (Q9P0U3)
Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1)
Gene: SENP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 16553580, 27449295, 21930380, 25412743, 27344494, 17099698, 25027693
Identification Methods enzymatic study, x-ray crystallography, fluorescent resonance energy transfer, pull down
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_C48~RanGAP1_C
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0016925 - protein sumoylation
GO:0031965 - nuclear membrane
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 587
Hs

1 644
+ Hs
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024