Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: STAT4 (Q14765)
Signal transducer and activator of transcription 4
Gene: STAT4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.767

The method score is based on:

Property Details
Experiments 25814554, unassigned1126
Identification Methods two hybrid, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH2, SH2~SH3_1, SH2~SH3_2
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 304
Hs

1 748
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024