HitPredict

Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: SNX7 (Q9UNH6)
Sorting nexin-7
Gene: SNX7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 304 Hs			1 387
+	Hs
		581079 PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39		SNX7_HUMAN (1-387): 7.12e-109: 326: 100.00
+	Hs
		924952 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		SNX7_HUMAN (1-387): 7.12e-109: 326: 100.00
+	Hs
		1167842 DNMBP_HUMAN (119-293): 5.7e-46: 168: 29.35		SNX9_HUMAN (28-373): 4e-78: 253: 16.34
+	Hs
		1167815 DNMBP_HUMAN (119-293): 5.7e-46: 168: 29.35		SNX33_HUMAN (22-377): 1.19e-77: 251: 15.68
+	Hs
		557829 NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00		SNX7_HUMAN (1-387): 7.12e-109: 326: 100.00
+	Hs
		234919 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		SNX3_HUMAN (26-147): 1.26e-46: 158: 34.65
+	Mm
		1141156 GRB2_MOUSE (135-297): 1.43e-25: 103: 15.67		SNX18_MOUSE (22-377): 3.97e-82: 264: 16.58
+	Hs
		275222 GRAP2_HUMAN (1-296): 5.17e-33: 125: 17.17		SNX18_HUMAN (22-295): 2.68e-60: 207: 17.81
+	Hs
		924801 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		SNX18_HUMAN (22-295): 2.68e-60: 207: 17.81
+	Hs
		1078937 ITSN1_HUMAN (150-302): 3.02e-10: 63.3: 13.87		SNX5_HUMAN (29-376): 1.85e-67: 220: 18.42
+	Hs
		1078933 ITSN1_HUMAN (150-302): 3.02e-10: 63.3: 13.87		SNX6_HUMAN (25-376): 3.02e-63: 209: 16.15
+	Hs
		234938 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		SNX3_HUMAN (26-147): 1.26e-46: 158: 34.65
+	Hs
		924951 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		SNX12_HUMAN (26-153): 8.22e-46: 156: 33.08
+	Hs
		234898 NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00		SNX3_HUMAN (26-147): 1.26e-46: 158: 34.65
+	Hs
		557828 NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00		SNX12_HUMAN (26-153): 8.22e-46: 156: 33.08
+	Hs
		581087 PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39		SNX11_HUMAN (48-147): 1.97e-09: 59.7: 31.00