HitPredict

Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: DLGP4 (Q9Y2H0)
Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4)
Gene: DLGAP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0031594 - neuromuscular junction
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 304 Hs			1 992
+	Hs
		145942 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		924968 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Hs
		209192 NCK2_HUMAN (2-100): 3.06e-11: 65.2: 18.00		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Hs
		557837 NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Hs
		145937 PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		802758 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		145943 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		145955 ITSN2_HUMAN (189-304): 5.82e-12: 68.3: 11.86		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		145936 NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		145950 ITSN1_HUMAN (150-302): 3.02e-10: 63.3: 13.87		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Mm
		1246939 SH3K1_MOUSE (114-186): 2.23e-10: 63.3: 21.33		DLGP1_MOUSE (1-992): 0: 1144: 45.61
+	Hs
		327231 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Hs
		4616 PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39		A0A1B0GTN4_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		581066 PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		924914 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		557812 NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		327226 PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Hs
		327232 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Hs
		327225 NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00		DLGP3_HUMAN (1-992): 0: 986: 35.35