HitPredict

Interactor 1: BAG6 (P46379)
Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe)
Gene: BAG6

Interactor 2: H3C (Q6NXT2)
Histone H3.3C (Histone H3.5)
Gene: H3-5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1132 Hs			1 135
+	Hs
		803604 BAG6_HUMAN (1-1132): 0: 597: 100.00		H32_HUMAN (1-135): 5.98e-56: 172: 93.38
+	Hs
		923949 RS27A_HUMAN (17-87): 2.18e-27: 111: 34.72		H31_HUMAN (1-135): 4.22e-57: 175: 92.65
+	Hs
		924266 RL40_HUMAN (17-87): 9.53e-28: 111: 34.72		H31_HUMAN (1-135): 4.22e-57: 175: 92.65
+	Hs
		924016 RS27A_HUMAN (17-87): 2.18e-27: 111: 34.72		H31T_HUMAN (1-135): 2.09e-56: 173: 89.71
+	Hs
		924314 RL40_HUMAN (17-87): 9.53e-28: 111: 34.72		H31T_HUMAN (1-135): 2.09e-56: 173: 89.71
+	Hs
		924046 RS27A_HUMAN (17-87): 2.18e-27: 111: 34.72		H32_HUMAN (1-135): 5.98e-56: 172: 93.38
+	Hs
		924330 RL40_HUMAN (17-87): 9.53e-28: 111: 34.72		H32_HUMAN (1-135): 5.98e-56: 172: 93.38
+	Hs
		935004 KMT2C_HUMAN (269-805): 1.24e-13: 78.2: 9.11		H31_HUMAN (1-135): 4.22e-57: 175: 92.65
+	Hs
		952479 KMT2C_HUMAN (269-805): 1.24e-13: 78.2: 9.11		H33_HUMAN (1-135): 1.39e-56: 174: 94.85
+	Hs
		1086228 KMT2C_HUMAN (269-805): 1.24e-13: 78.2: 9.11		H31T_HUMAN (1-135): 2.09e-56: 173: 89.71
+	Hs
		1174600 KMT2C_HUMAN (269-805): 1.24e-13: 78.2: 9.11		H32_HUMAN (1-135): 5.98e-56: 172: 93.38
+	Mm
		101827 F8WI37_MOUSE (278-784): 7.81e-12: 72.5: 10.40		H33_MOUSE (1-135): 1.39e-56: 174: 94.85
+	Hs
		935324 CHD7_HUMAN (52-409): 9.99e-10: 65.5: 8.64		H31_HUMAN (1-135): 4.22e-57: 175: 92.65
+	Hs
		935066 CBP_HUMAN (204-749): 1.19e-09: 65.1: 12.25		H31_HUMAN (1-135): 4.22e-57: 175: 92.65
+	Hs
		952670 CHD7_HUMAN (52-409): 9.99e-10: 65.5: 8.64		H33_HUMAN (1-135): 1.39e-56: 174: 94.85
+	Hs
		1086253 CBP_HUMAN (204-749): 1.19e-09: 65.1: 12.25		H31T_HUMAN (1-135): 2.09e-56: 173: 89.71
+	Hs
		828410 CHD7_HUMAN (52-409): 9.99e-10: 65.5: 8.64		CENPA_HUMAN (9-132): 2.48e-39: 130: 47.69