HitPredict

Interactor 1: NSF (P46459)
Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF)
Gene: NSF

Interactor 2: SNAA (P54920)
Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein alpha)
Gene: NAPA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.950

The method score is based on:

Property Details
Experiments 30833792, 9362506, 7622514, 35271311, 20562859, 15322554
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, chromatography technology
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC48_N~SNAP
Common GO terms GO:0000149 - SNARE binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006886 - intracellular protein transport
GO:0006891 - intra-Golgi vesicle-mediated transport
and 2 others

more...
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 744
Hs

1 295
+ Dm
+ Dm
+ Hs
+ Dd
+ Sc
+ Dm
+ Dm
+ Dd
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024