HitPredict

Interactor 1: NSF (P46459)
Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF)
Gene: NSF

Interactor 2: PTN12 (Q05209)
Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (PTP-PEST) (Protein-tyrosine phosphatase G1) (PTPG1)
Gene: PTPN12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	19167335
Identification Methods	phosphatase assay
Interaction Type	dephosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 744 Hs			1 780
+	Hs
		441189 NSF_HUMAN (1-744): 0: 572: 100.00		PTPRC_HUMAN (13-678): 1.57e-143: 456: 19.30
+	Hs
		616909 NSF_HUMAN (1-744): 0: 572: 100.00		PTPRB_HUMAN (7-314): 1.22e-123: 410: 29.62
+	Mm
		192449 NSF_MOUSE (1-744): 0: 574: 98.12		PTN9_MOUSE (3-306): 4.49e-124: 385: 31.66
+	Rn
		1145114 NSF_RAT (1-744): 0: 572: 97.85		PTN9_RAT (3-306): 7.98e-124: 385: 31.66
+	Hs
		796392 NSF_HUMAN (1-744): 0: 572: 100.00		PTN9_HUMAN (3-306): 5.55e-124: 385: 31.98
+	Hs
		803919 NSF_HUMAN (1-744): 0: 572: 100.00		PTPRK_HUMAN (17-297): 1.82e-59: 221: 26.64
+	Hs
		617088 NSF_HUMAN (1-744): 0: 572: 100.00		PTPRG_HUMAN (8-299): 1.84e-52: 200: 24.50
+	Hs
		803926 NSF_HUMAN (1-744): 0: 572: 100.00		PTPRO_HUMAN (58-303): 3.31e-46: 180: 38.71
+	Hs
		803903 NSF_HUMAN (1-744): 0: 572: 100.00		PTPRJ_HUMAN (49-297): 6.23e-46: 179: 39.13
+	Hs
		875454 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		PTN22_HUMAN (1-779): 6.27e-132: 413: 32.01
+	Hs
		874858 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		PTN11_HUMAN (7-351): 1.65e-124: 387: 31.48
+	Hs
		796395 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		PTN9_HUMAN (3-306): 5.55e-124: 385: 31.98
+	Hs
		577006 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		PTPRA_HUMAN (7-295): 5.6e-105: 342: 32.08
+	Hs
		660842 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		PTPRM_HUMAN (7-296): 8.79e-62: 228: 24.50
+	Hs
		875174 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		PTPRU_HUMAN (7-293): 8.06e-59: 219: 21.36
+	Hs
		874988 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		PTPRO_HUMAN (58-303): 3.31e-46: 180: 38.71