HitPredict

Interactor 1: RHBT3 (O94955)
Rho-related BTB domain-containing protein 3 (EC 3.6.1.-)
Gene: RHOBTB3

Interactor 2: TNR6 (P25445)
Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95)
Gene: FAS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 611 Hs			1 335
+	Hs
		301223 RHBT3_HUMAN (1-611): 1.41e-158: 469: 100.00		TR19L_HUMAN (62-161): 5.58e-16: 80.3: 26.47
+	Hs
		301199 RHBT3_HUMAN (1-611): 1.41e-158: 469: 100.00		TNR9_HUMAN (60-209): 5.96e-16: 78.4: 16.77
+	Hs
		632236 RHOA_HUMAN (29-204): 6.83e-65: 213: 17.55		TNR6_HUMAN (1-335): 2.61e-113: 333: 100.00
+	Hs
		738654 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		TNR3_HUMAN (42-245): 1.27e-42: 154: 21.80
+	Hs
		584368 RAC1_HUMAN (31-206): 5.82e-66: 215: 20.75		TNR1A_HUMAN (22-202): 6.36e-42: 153: 20.65
+	Hs
		738655 RHOA_HUMAN (29-204): 6.83e-65: 213: 17.55		TNR3_HUMAN (42-245): 1.27e-42: 154: 21.80
+	Hs
		584359 RHOA_HUMAN (29-204): 6.83e-65: 213: 17.55		TNR1A_HUMAN (22-202): 6.36e-42: 153: 20.65
+	Hs
		121466 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		TR10A_HUMAN (44-177): 4.43e-31: 123: 27.01
+	Hs
		154333 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		TR10B_HUMAN (42-216): 2.84e-31: 123: 21.91
+	Hs
		267341 RAC3_HUMAN (31-196): 1.39e-65: 214: 19.10		TNR21_HUMAN (39-230): 1.71e-32: 129: 15.90
+	Hs
		121470 RAC1_HUMAN (31-206): 5.82e-66: 215: 20.75		TR10A_HUMAN (44-177): 4.43e-31: 123: 27.01
+	Hs
		154338 RAC1_HUMAN (31-206): 5.82e-66: 215: 20.75		TR10B_HUMAN (42-216): 2.84e-31: 123: 21.91
+	Hs
		121464 RAC3_HUMAN (31-196): 1.39e-65: 214: 19.10		TR10A_HUMAN (44-177): 4.43e-31: 123: 27.01
+	Hs
		154332 RAC3_HUMAN (31-196): 1.39e-65: 214: 19.10		TR10B_HUMAN (42-216): 2.84e-31: 123: 21.91
+	Hs
		121467 RHOA_HUMAN (29-204): 6.83e-65: 213: 17.55		TR10A_HUMAN (44-177): 4.43e-31: 123: 27.01
+	Hs
		154335 RHOA_HUMAN (29-204): 6.83e-65: 213: 17.55		TR10B_HUMAN (42-216): 2.84e-31: 123: 21.91
+	Hs
		121436 RAC2_HUMAN (31-205): 2.83e-64: 211: 19.25		TR10A_HUMAN (44-177): 4.43e-31: 123: 27.01
+	Hs
		154300 RAC2_HUMAN (31-205): 2.83e-64: 211: 19.25		TR10B_HUMAN (42-216): 2.84e-31: 123: 21.91
+	Hs
		925501 RAC1_HUMAN (31-206): 5.82e-66: 215: 20.75		TR19L_HUMAN (62-161): 5.58e-16: 80.3: 26.47