Interactor 1: NOTC1 (P46531)
Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: NOTCH1
Interactor 2: ATM (Q13315)
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
Gene: ATM
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.57 | 1.00 | 0.757 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25895060 |
| Identification Methods | anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ank_2~FAT |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0007507 - heart development GO:0010628 - positive regulation of gene expression and 2 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
