Interactor 1: NOTC1 (P46531)
Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: NOTCH1

Interactor 2: ILK (Q13418)
Integrin-linked protein kinase (EC 2.7.11.1) (59 kDa serine/threonine-protein kinase) (Beta-integrin-linked kinase) (ILK-1) (ILK-2) (p59ILK)
Gene: ILK

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 17526737
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Ank_2, Ank_2~Ank_2, Ank_2~Ank_4
Common GO terms GO:0003151 - outflow tract morphogenesis
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008284 - positive regulation of cell population proliferation
GO:0030513 - positive regulation of BMP signaling pathway
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 2555
Hs

1 452
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024