Interactor 1: NOTC1 (P46531)
Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: NOTCH1
Interactor 2: MAML2 (Q8IZL2)
Mastermind-like protein 2 (Mam-2)
Gene: MAML2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.723 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12370315 |
| Identification Methods | two hybrid, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ank_2~MamL-1 |
| Common GO terms | GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0007219 - Notch signaling pathway GO:0007221 - positive regulation of transcription of Notch receptor target and 1 others more... |
| Homologous interactions | 10 |
Homologous interactions
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Last updated: 15 Jul 2024
