Interactor 1: BRCC3 (P46736)
Lys-63-specific deubiquitinase BRCC36 (EC 3.4.19.-) (BRCA1-A complex subunit BRCC36) (BRCA1/BRCA2-containing complex subunit 3) (BRCA1/BRCA2-containing complex subunit 36) (BRISC complex subunit BRCC36)
Gene: BRCC3

Interactor 2: BRCC3 (P46736)
Lys-63-specific deubiquitinase BRCC36 (EC 3.4.19.-) (BRCA1-A complex subunit BRCC36) (BRCA1/BRCA2-containing complex subunit 3) (BRCA1/BRCA2-containing complex subunit 36) (BRISC complex subunit BRCC36)
Gene: BRCC3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 21282113
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BRCC36_C~BRCC36_C, BRCC36_C~JAB, JAB~JAB
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0000152 - nuclear ubiquitin ligase complex
GO:0000922 - spindle pole
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
and 25 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 316
Hs

1 316
+ Hs
+ Ce
+ Zm
+ Hs
+ Ce
+ Sc
+ Hs
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024