Interactor 1: BRCC3 (P46736)
Lys-63-specific deubiquitinase BRCC36 (EC 3.4.19.-) (BRCA1-A complex subunit BRCC36) (BRCA1/BRCA2-containing complex subunit 3) (BRCA1/BRCA2-containing complex subunit 36) (BRISC complex subunit BRCC36)
Gene: BRCC3

Interactor 2: UIMC1 (Q96RL1)
BRCA1-A complex subunit RAP80 (Receptor-associated protein 80) (Retinoid X receptor-interacting protein 110) (Ubiquitin interaction motif-containing protein 1)
Gene: UIMC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.55 0.728

The method score is based on:

Property Details
Experiments 35938958, 19615732, 18077395, 21282113, 20656689, 19261748, 19202061, 17525341, 19261749, 19261746, 19305427, 19015238, 23264621
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006282 - regulation of DNA repair
GO:0006302 - double-strand break repair
GO:0007095 - mitotic G2 DNA damage checkpoint signaling
and 6 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024