Interactor 1: STT3 (P39007)
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3 (Oligosaccharyl transferase subunit STT3) (EC 2.4.99.18) (Staurosporine and temperature sensitivity protein 3)
Gene: STT3

Interactor 2: OST1 (P41543)
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (N-linked oligosaccharyl transferase subunit 1) (Oligosaccharyl transferase 64 kDa subunit) (Oligosaccharyl transferase subunit OST1) (Oligosaccharyl transferase subunit alpha)
Gene: OST1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 9435788, 9405463, 11805826, 12805367, 16096346, 32938717, 37968396, 31851481, 16429126, 14530272
Identification Methods affinity chromatography technology, coimmunoprecipitation, tandem affinity purification, biochemical, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ribophorin_I~STT3
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006487 - protein N-linked glycosylation
GO:0008250 - oligosaccharyltransferase complex
GO:0018279 - protein N-linked glycosylation via asparagine
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 718
Sc

1 476
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025