Interactor 1: RPN1 (P04843)
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit) (Ribophorin I) (RPN-I) (Ribophorin-1)
Gene: RPN1

Interactor 2: STT3A (P46977)
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (Oligosaccharyl transferase subunit STT3A) (STT3-A) (EC 2.4.99.18) (B5) (Integral membrane protein 1) (Transmembrane protein TMC)
Gene: STT3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 35271311, 31839598, 30021884, 32788342, 34079125, 35235311, 37071682, 39358380, 40437099
Identification Methods affinity chromatography technology, cross-linking study, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AglB_core-like~Ribophorin_I, Ribophorin_I~STT3
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0006487 - protein N-linked glycosylation
GO:0008250 - oligosaccharyltransferase complex
GO:0016020 - membrane
GO:0018279 - protein N-linked glycosylation via asparagine
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 607
Hs

1 705
+ Hs
+ Sc

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Last updated: 11Aug2025