HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: KDM2A (Q9Y2K7)
Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A)
Gene: KDM2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38280479
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 1162
+	Hs
		808329 NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26		KDM2A_HUMAN (1-1162): 0: 1354: 100.00
+	Hs
		808783 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		KDM2B_HUMAN (15-1162): 0: 1040: 37.75
+	Hs
		125793 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		PHF8_HUMAN (12-406): 1.45e-164: 517: 37.69
+	Hs
		1299662 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		PHF8_HUMAN (12-406): 1.45e-164: 517: 37.69
+	Hs
		809026 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PHF8_HUMAN (12-406): 1.45e-164: 517: 37.69
+	Hs
		808533 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		KMT2A_HUMAN (360-609): 1.68e-47: 188: 20.73
+	Hs
		808574 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		SKP2_HUMAN (805-1151): 6.12e-48: 179: 19.24
+	Hs
		1336111 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		FBXL2_HUMAN (898-1149): 9.38e-43: 163: 19.78
+	Hs
		125710 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		FXL15_HUMAN (861-1146): 7.97e-12: 69.4: 18.90
+	Hs
		1294860 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		FXL15_HUMAN (861-1146): 7.97e-12: 69.4: 18.90
+	Hs
		1299633 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		FXL15_HUMAN (861-1146): 7.97e-12: 69.4: 18.90
+	Hs
		1330594 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		FXL15_HUMAN (861-1146): 7.97e-12: 69.4: 18.90
+	Hs
		1327912 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		FXL15_HUMAN (861-1146): 7.97e-12: 69.4: 18.90
+	Hs
		808271 NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26		FXL15_HUMAN (861-1146): 7.97e-12: 69.4: 18.90
+	Hs
		1330593 SMUF2_HUMAN (99-504): 4.95e-107: 337: 19.19		FXL15_HUMAN (861-1146): 7.97e-12: 69.4: 18.90
+	Hs
		975321 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		KMT2A_HUMAN (360-609): 1.68e-47: 188: 20.73
+	Hs
		975337 HECW2_HUMAN (13-303): 1.56e-14: 79: 14.79		KMT2A_HUMAN (360-609): 1.68e-47: 188: 20.73
+	Hs
		1176348 HECW1_HUMAN (2-222): 1.33e-24: 110: 14.96		FXL15_HUMAN (861-1146): 7.97e-12: 69.4: 18.90
+	Hs
		1330595 HECW2_HUMAN (13-303): 1.56e-14: 79: 14.79		FXL15_HUMAN (861-1146): 7.97e-12: 69.4: 18.90