Protein: CNOT7
CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (BTG1-binding factor 1) (CCR4-associated factor 1) (CAF-1) (Caf1a)

Gene: CNOT7
Organism: Homo sapiens
Interactions: 137
UniProt ID: Q9UIV1

Gene Ontology (top 5):
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000932 - P-body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

897476

TOB1
Protein Tob1

10

20

Small-scale

0.974

High

1120432

TOB2
Protein Tob2

7

20

Small-scale

0.973

High

64146

CNOT1
CCR4-NOT transcription complex subunit 1

8

8

Small-scale

0.972

High

974909

BTG1
Protein BTG1

6

20

Small-scale

0.945

High

1008536

BTG2
Protein BTG2

5

20

Small-scale

0.934

High

1123549

BTG3
Protein BTG3

3

20

High-throughput

0.861

High

1397047

CNO6L
CCR4-NOT transcription complex subunit 6-like

9

13

Small-scale

0.752

High

1460492

CNOT6
CCR4-NOT transcription complex subunit 6

8

13

Small-scale

0.746

High

1453506

CNOT2
CCR4-NOT transcription complex subunit 2

6

10

High-throughput

0.730

High

1420828

TB182
182 kDa tankyrase-1-binding protein

6

2

Small-scale

0.729

High

1460490

CNO11
CCR4-NOT transcription complex subunit 11

6

1

High-throughput

0.729

High

1215884

RC3H1
Roquin-1

6

4

Small-scale

0.721

High

273947

CNOT3
CCR4-NOT transcription complex subunit 3

5

13

High-throughput

0.712

High

1336875

TNR6A
Trinucleotide repeat-containing gene 6A protein

4

6

Small-scale

0.696

High

1314169

RAVR1
Ribonucleoprotein PTB-binding 1

4

3

High-throughput

0.694

High

1365385

CNOT9
CCR4-NOT transcription complex subunit 9

4

5

High-throughput

0.694

High

1436894

CNO10
CCR4-NOT transcription complex subunit 10

4

1

High-throughput

0.694

High

866858

CAZA2
F-actin-capping protein subunit alpha-2

4

3

High-throughput

0.691

High

550509

PABP1
Polyadenylate-binding protein 1

3

2

Small-scale

0.664

High

1460497

ARIP4
Helicase ARIP4

4

0

High-throughput

0.663

High

1439108

TNR6C
Trinucleotide repeat-containing gene 6C protein

3

8

Small-scale

0.662

High

1460489

AGO2
Protein argonaute-2

3

6

Small-scale

0.656

High

867496

CAPZB
F-actin-capping protein subunit beta

3

1

High-throughput

0.650

High

1438072

RC3H2
Roquin-2

3

6

Small-scale

0.640

High

1400980

PURB
Transcriptional regulator protein Pur-beta

3

0

High-throughput

0.638

High

275467

GA45B
Growth arrest and DNA damage-inducible protein GADD45 beta

2

1

High-throughput

0.628

High

949509

NANO2
Nanos homolog 2

2

4

High-throughput

0.628

High

844069

HD
Huntingtin

2

2

High-throughput

0.621

High

1116105

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

2

4

High-throughput

0.611

High

1438635

GPBL1
Vasculin-like protein 1

2

2

High-throughput

0.611

High

480393

MMP7
Matrilysin

3

1

High-throughput

0.609

High

1325729

RIBC1
RIB43A-like with coiled-coils protein 1

3

1

High-throughput

0.604

High

1326456

MINK1
Misshapen-like kinase 1

2

0

High-throughput

0.602

High

1460493

TNR6B
Trinucleotide repeat-containing gene 6B protein

2

6

Small-scale

0.601

High

1287145

PATL1
Protein PAT1 homolog 1

2

4

Small-scale

0.594

High

1233696

Q6IBC8
Protein BTG1

1

20

High-throughput

0.590

High

549257

CDK4
Cyclin-dependent kinase 4

2

2

Small-scale

0.586

High

688335

TTP
mRNA decay activator protein ZFP36

2

6

Small-scale

0.584

High

1217025

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

2

3

Small-scale

0.584

High

1310670

Z3H7A
Zinc finger CCCH domain-containing protein 7A

2

1

High-throughput

0.584

High

1417397

TX13A
Testis-expressed protein 13A

2

1

High-throughput

0.574

High

397171

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

352583

TOP3B
DNA topoisomerase 3-beta-1

2

0

High-throughput

0.559

High

1399947

FACOS
FANCD2 opposite strand protein

2

1

High-throughput

0.549

High

1219906

OBI1
ORC ubiquitin ligase 1

2

1

Small-scale

0.543

High

1460500

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.537

High

64816

EPAB2
Embryonic polyadenylate-binding protein 2

1

2

High-throughput

0.536

High

302094

SEGN
Secretagogin

1

1

High-throughput

0.536

High

638550

FPR1
fMet-Leu-Phe receptor

1

1

High-throughput

0.536

High

848742

MAGA9
Melanoma-associated antigen 9

1

1

High-throughput

0.536

High

915213

CAZA1
F-actin-capping protein subunit alpha-1

1

3

High-throughput

0.536

High

1123168

FHL2
Four and a half LIM domains protein 2

1

2

High-throughput

0.536

High

1347605

UHMK1
Serine/threonine-protein kinase Kist

1

3

High-throughput

0.536

High

1361409

NANO1
Nanos homolog 1

1

4

High-throughput

0.536

High

1364170

TM131
Transmembrane protein 131

1

3

High-throughput

0.536

High

1460491

AGO1
Protein argonaute-1

1

6

Small-scale

0.536

High

478305

HXD4
Homeobox protein Hox-D4

1

0

High-throughput

0.518

High

296842

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.513

High

854374

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

890071

PSN1
Presenilin-1

1

0

High-throughput

0.513

High

902906

BLK
Tyrosine-protein kinase Blk

1

0

High-throughput

0.513

High

1405997

C10
Protein C10

1

0

High-throughput

0.513

High

1435419

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

1337110

CPEB3
Cytoplasmic polyadenylation element-binding protein 3

1

7

Small-scale

0.484

High

778802

PRS7
26S proteasome regulatory subunit 7

1

1

High-throughput

0.481

High

1116616

FHL3
Four and a half LIM domains protein 3

1

2

High-throughput

0.481

High

1408313

FOXC2
Forkhead box protein C2

1

2

High-throughput

0.481

High

423415

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

1460496

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

50425

MEX3A
RNA-binding protein MEX3A

1

3

Small-scale

0.479

High

170410

AURKA
Aurora kinase A

1

1

High-throughput

0.479

High

173519

XPO1
Exportin-1

1

1

High-throughput

0.479

High

176567

GRRE1
Granule associated Rac and RHOG effector protein 1

1

1

High-throughput

0.479

High

274256

ANR17
Ankyrin repeat domain-containing protein 17

1

1

High-throughput

0.479

High

340595

CNOT4
CCR4-NOT transcription complex subunit 4

1

3

High-throughput

0.479

High

443550

CDK1
Cyclin-dependent kinase 1

1

1

Small-scale

0.479

High

626393

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

2

High-throughput

0.479

High

651454

CBL
E3 ubiquitin-protein ligase CBL

1

2

High-throughput

0.479

High

668066

CDK2
Cyclin-dependent kinase 2

1

1

Small-scale

0.479

High

684428

DDX6
Probable ATP-dependent RNA helicase DDX6

1

3

High-throughput

0.479

High

713868

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

3

High-throughput

0.479

High

838196

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

1

Small-scale

0.479

High

875820

PRC2A
Protein PRRC2A

1

1

High-throughput

0.479

High

1129530

PUM1
Pumilio homolog 1

1

9

High-throughput

0.479

High

1165522

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

7

High-throughput

0.479

High

1208597

SMAG2
Protein Smaug homolog 2

1

1

High-throughput

0.479

High

1252411

MEX3B
RNA-binding protein MEX3B

1

3

High-throughput

0.479

High

1280766

YTHD3
YTH domain-containing family protein 3

1

6

High-throughput

0.479

High

1292631

GPBP1
Vasculin

1

2

High-throughput

0.479

High

1360840

ASB11
Ankyrin repeat and SOCS box protein 11

1

2

High-throughput

0.479

High

1364005

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

1

High-throughput

0.479

High

1367533

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

1395783

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

1

High-throughput

0.479

High

1418753

YTHD1
YTH domain-containing family protein 1

1

6

High-throughput

0.479

High

1419550

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

5

High-throughput

0.479

High

1420677

UNK
RING finger protein unkempt homolog

1

6

High-throughput

0.479

High

1437075

AGO3
Protein argonaute-3

1

6

High-throughput

0.479

High

1460494

SMG5
Nonsense-mediated mRNA decay factor SMG5

1

1

High-throughput

0.479

High

1460495

R3HD2
R3H domain-containing protein 2

1

2

High-throughput

0.479

High

1460498

YTHD2
YTH domain-containing family protein 2

1

6

High-throughput

0.479

High

297710

PIAS1
E3 SUMO-protein ligase PIAS1

1

0

High-throughput

0.460

High

968828

PRS4
26S proteasome regulatory subunit 4

1

0

High-throughput

0.460

High

974291

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

0

High-throughput

0.460

High

1101247

NMI
N-myc-interactor

1

0

High-throughput

0.460

High

1407494

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.460

High

1447955

SHLB2
Endophilin-B2

1

0

High-throughput

0.460

High

347984

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

696805

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

998924

H31
Histone H3.1

1

0

Small-scale

0.458

High

1192964

PAR14
Protein mono-ADP-ribosyltransferase PARP14

1

0

High-throughput

0.458

High

1241603

CEP85
Centrosomal protein of 85 kDa

1

0

High-throughput

0.458

High

1256003

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1289206

N4BP2
NEDD4-binding protein 2

1

0

High-throughput

0.458

High

1322809

CNTRB
Centrobin

1

0

High-throughput

0.458

High

1327744

MACOI
Macoilin

1

0

High-throughput

0.458

High

1371471

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

0

High-throughput

0.458

High

1407430

EPAS1
Endothelial PAS domain-containing protein 1

1

0

Small-scale

0.458

High

1409557

B9D2
B9 domain-containing protein 2

1

0

High-throughput

0.458

High

1416759

BBS2
BBSome complex member BBS2

1

0

High-throughput

0.458

High

1435699

TDRD3
Tudor domain-containing protein 3

1

0

High-throughput

0.458

High

1448115

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.458

High

1453028

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1459230

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1460488

FBW1B
F-box/WD repeat-containing protein 11

1

0

High-throughput

0.458

High

1460499

HCFC2
Host cell factor 2

1

0

High-throughput

0.458

High

1206568

PRC2B
Protein PRRC2B

1

1

High-throughput

0.437

High

1034541

TAGL
Transgelin

1

0

High-throughput

0.426

High

1306929

DCP2
m7GpppN-mRNA hydrolase

1

0

Small-scale

0.426

High

1448543

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.426

High

94353

D6R9H6
CCR4-NOT transcription complex subunit 6

1

13

High-throughput

0.407

High

1449851

T11L1
T-complex protein 11-like protein 1

2

0

High-throughput

0.316

High

1160962

PDK4
[Pyruvate dehydrogenase

1

0

High-throughput

0.279

Low

1192027

AX2R
Annexin-2 receptor

1

0

High-throughput

0.279

Low

1231158

SCAR3
Scavenger receptor class A member 3

1

0

High-throughput

0.265

Low

1315005

TEX11
Testis-expressed protein 11

1

0

High-throughput

0.251

Low

1393550

MR1L1
MORF4 family-associated protein 1-like 1

1

0

High-throughput

0.251

Low

1004300

F193A
Protein FAM193A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025