HitPredict

Interactor 1: MSS4 (P47224)
Guanine nucleotide exchange factor MSS4 (Rab-interacting factor)
Gene: RABIF

Interactor 2: RAP1A (P62834)
Ras-related protein Rap-1A (EC 3.6.5.2) (C21KG) (G-22K) (GTP-binding protein smg p21A) (Ras-related protein Krev-1)
Gene: RAP1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Mss4~Ras
Common GO terms	GO:0005085 - guanyl-nucleotide exchange factor activity GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 123 Hs			1 184
+	Hs
		812737 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB1A_HUMAN (4-183): 2.18e-73: 221: 31.49
+	Mm
		918998 MSS4_MOUSE (1-123): 1.15e-71: 211: 93.50		RAB1A_MOUSE (4-183): 2.18e-73: 221: 31.49
+	Hs
		812757 MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00		RAB1B_HUMAN (4-179): 2.82e-72: 218: 30.51
+	Dm
		185502 MSS4_DROME (13-123): 3.14e-52: 162: 39.29		O18332_DROME (4-180): 2.86e-71: 216: 33.71