HitPredict

Interactor 1: TNR4 (P47741)
Tumor necrosis factor receptor superfamily member 4 (OX40 antigen) (OX40L receptor) (CD antigen CD134)
Gene: Tnfrsf4

Interactor 2: IKKA (Q60680)
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA)
Gene: Chuk

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	21282629
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 272 Mm			1 745
+	Mm
		291445 TNR4_MOUSE (1-272): 8.53e-66: 208: 100.00		IKKB_MOUSE (1-743): 0: 600: 48.73
+	Hs
		167470 TNR1B_HUMAN (3-233): 9.27e-38: 139: 22.85		IKKA_HUMAN (1-745): 0: 600: 95.44
+	Hs
		167467 TNR1A_HUMAN (8-253): 3.98e-37: 138: 18.97		IKKA_HUMAN (1-745): 0: 600: 95.44
+	Hs
		167447 TNR16_HUMAN (27-240): 1.2e-36: 136: 22.40		IKKA_HUMAN (1-745): 0: 600: 95.44
+	Hs
		158391 TNR1A_HUMAN (8-253): 3.98e-37: 138: 18.97		IKKB_HUMAN (1-743): 0: 597: 49.93
+	Hs
		158372 TNR16_HUMAN (27-240): 1.2e-36: 136: 22.40		IKKB_HUMAN (1-743): 0: 597: 49.93
+	Mm
		291437 TNR1A_MOUSE (8-241): 5.1e-33: 127: 22.41		IKKB_MOUSE (1-743): 0: 600: 48.73
+	Mm
		626859 TNR1A_MOUSE (8-241): 5.1e-33: 127: 22.41		IKKA_MOUSE (1-745): 0: 597: 100.00
+	Hs
		167489 TNR3_HUMAN (15-173): 5.62e-30: 118: 26.49		IKKA_HUMAN (1-745): 0: 600: 95.44
+	Hs
		158417 TNR3_HUMAN (15-173): 5.62e-30: 118: 26.49		IKKB_HUMAN (1-743): 0: 597: 49.93
+	Mm
		291439 TNR5_MOUSE (10-174): 3.07e-29: 113: 27.13		IKKB_MOUSE (1-743): 0: 600: 48.73
+	Mm
		648957 TNR5_MOUSE (10-174): 3.07e-29: 113: 27.13		IKKA_MOUSE (1-745): 0: 597: 100.00
+	Hs
		167474 TNR5_HUMAN (10-173): 9.09e-28: 109: 26.20		IKKA_HUMAN (1-745): 0: 600: 95.44
+	Hs
		158399 TNR5_HUMAN (10-173): 9.09e-28: 109: 26.20		IKKB_HUMAN (1-743): 0: 597: 49.93
+	Hs
		584494 TNR1A_HUMAN (8-253): 3.98e-37: 138: 18.97		TBK1_HUMAN (15-679): 2.12e-122: 384: 19.52
+	Hs
		584404 TNR1A_HUMAN (8-253): 3.98e-37: 138: 18.97		IKKE_HUMAN (15-730): 3.98e-121: 381: 19.50
+	Hs
		632369 TNR6_HUMAN (13-140): 2.76e-29: 114: 27.61		M3K5_HUMAN (14-729): 4.15e-121: 396: 19.11
+	Hs
		436609 TNR16_HUMAN (27-240): 1.2e-36: 136: 22.40		KAPCB_HUMAN (5-329): 4.99e-90: 288: 26.06