Protein: OST1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (N-linked oligosaccharyl transferase subunit 1) (Oligosaccharyl transferase 64 kDa subunit) (Oligosaccharyl transferase subunit OST1) (Oligosaccharyl transferase subunit alpha)

Gene: OST1
Organism: Saccharomyces cerevisiae S288C
Interactions: 63
UniProt ID: P41543

Gene Ontology (top 5):
GO:0005198 - structural molecule activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006487 - protein N-linked glycosylation
GO:0006488 - dolichol-linked oligosaccharide biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

754632

OSTB
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1

13

3

Small-scale

0.978

High

809019

STT3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3

10

2

Small-scale

0.968

High

835073

OST5
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST5

3

0

Small-scale

0.784

High

835066

OST6
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST6

7

3

Small-scale

0.740

High

835058

OST3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3

8

3

Small-scale

0.739

High

835064

OSTD
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1

8

0

Small-scale

0.714

High

835075

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST4

7

0

Small-scale

0.709

High

835055

OST2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2

4

1

Small-scale

0.672

High

835065

ERO1
Endoplasmic oxidoreductin-1

2

0

High-throughput

0.595

High

835069

SEC13
Protein transport protein SEC13

2

2

High-throughput

0.588

High

835052

OST1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

2

1

Small-scale

0.586

High

835059

SC6B1
Protein transport protein SBH1

2

1

Small-scale

0.586

High

754697

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

2

1

Small-scale

0.584

High

821017

EIF3I
Eukaryotic translation initiation factor 3 subunit I

2

1

High-throughput

0.567

High

748435

SC61A
Protein transport protein SEC61

1

1

Small-scale

0.552

High

763156

SC61G
Protein transport protein SSS1

1

0

Small-scale

0.543

High

416711

CAN1
Arginine permease CAN1

1

4

High-throughput

0.541

High

835074

TECR
Very-long-chain enoyl-CoA reductase

1

3

High-throughput

0.541

High

835061

SEH1
Nucleoporin SEH1

2

2

High-throughput

0.537

High

835054

GPI2
Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit

1

0

High-throughput

0.518

High

835057

YJY5
Uncharacterized endoplasmic reticulum membrane protein YJR015W

1

0

High-throughput

0.518

High

802995

COS8
Protein COS8

1

1

High-throughput

0.494

High

812912

UIP3
ULP1-interacting protein 3

1

1

High-throughput

0.494

High

835060

SC6B2
Protein transport protein SBH2

1

1

Small-scale

0.481

High

835072

NPC1
NPC intracellular sterol transporter 1-related protein 1

1

3

Small-scale

0.481

High

577155

SEC63
Protein translocation protein SEC63

1

5

High-throughput

0.479

High

672160

ERG4
Delta(24(24(1)))-sterol reductase ERG4

1

3

High-throughput

0.479

High

726096

PMT2
Dolichyl-phosphate-mannose--protein mannosyltransferase 2

1

1

High-throughput

0.479

High

747683

MNS1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

2

High-throughput

0.479

High

818167

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

3

Small-scale

0.479

High

678011

CWH43
Protein CWH43

1

0

High-throughput

0.458

High

735845

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

Small-scale

0.458

High

796957

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

835067

CUE4
CUE domain-containing protein CUE4

1

0

High-throughput

0.458

High

672997

PHO87
Inorganic phosphate transporter PHO87

1

1

Small-scale

0.439

High

812846

PHO90
Low-affinity phosphate transporter PHO90

1

1

Small-scale

0.439

High

403547

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

1

High-throughput

0.437

High

665830

KPC1
Protein kinase C-like 1

1

2

Small-scale

0.437

High

670827

SIS1
Protein SIS1

1

1

High-throughput

0.437

High

486217

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.407

High

524248

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.407

High

526936

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.407

High

545226

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.407

High

592311

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.407

High

835053

EMW1
Essential for maintenance of the cell wall protein 1

1

1

High-throughput

0.407

High

477574

MYO1
Myosin-1

1

0

Small-scale

0.251

Low

623873

MYO2
Myosin-2

1

0

Small-scale

0.251

Low

835070

AUS1
ATP-dependent permease AUS1

1

0

Small-scale

0.251

Low

64253

YP010
UPF0495 protein YPR010C-A

1

0

Small-scale

0.249

Low

707366

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

752376

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.249

Low

763915

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

826574

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

835056

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

835062

PESC
Pescadillo homolog

1

0

High-throughput

0.249

Low

835063

HST2
NAD-dependent protein deacetylase HST2

1

0

High-throughput

0.249

Low

835068

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.249

Low

835071

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.249

Low

830000

LYS14
Lysine biosynthesis regulatory protein LYS14

1

0

High-throughput

0.238

Low

531779

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.232

Low

684755

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.232

Low

780115

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025