HitPredict

Interactor 1: CAZA2 (P47755)
F-actin-capping protein subunit alpha-2 (CapZ alpha-2)
Gene: CAPZA2

Interactor 2: SRC8 (Q14247)
Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Gene: CTTN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26496610, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030036 - actin cytoskeleton organization GO:0030863 - cortical cytoskeleton GO:0051015 - actin filament binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 286 Hs			1 550
+	Hs
		857125 CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71		SRC8_HUMAN (1-550): 0: 559: 100.00
+	Hs
		813005 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		MYO1E_HUMAN (165-549): 3.1e-44: 170: 15.01
+	Hs
		813018 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		SPTN1_HUMAN (213-549): 1.51e-33: 138: 14.12
+	Hs
		813199 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		DBNL_HUMAN (359-550): 8.22e-32: 129: 32.21
+	Hs
		298962 CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00		SRBS2_HUMAN (447-549): 1.56e-11: 69.2: 21.91