HitPredict

Interactor 1: KCNJ4 (P48050)
Inward rectifier potassium channel 4 (HIRK2) (HRK1) (Hippocampal inward rectifier) (HIR) (Inward rectifier K(+) channel Kir2.3) (IRK-3) (Potassium channel, inwardly rectifying subfamily J member 4)
Gene: KCNJ4

Interactor 2: SNTA1 (Q13424)
Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin-1)
Gene: SNTA1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.608

Property	Details
Experiments	15024025, 15123239
Identification Methods	affinity chromatography technology, unspecified method, peptide array
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030165 - PDZ domain binding GO:0045211 - postsynaptic membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 445 Hs			1 505
+	Hs
		1033833 KCJ12_HUMAN (7-445): 0: 660: 63.86		SNTA1_HUMAN (1-505): 2.08e-174: 502: 100.00
+	Hs
		1046429 KCJ12_HUMAN (7-445): 0: 660: 63.86		SNTB1_HUMAN (8-505): 9.95e-157: 458: 47.62
+	Hs
		1033871 KCJ12_HUMAN (7-445): 0: 660: 63.86		SNTB2_HUMAN (3-504): 3.86e-150: 441: 45.28
+	Hs
		816150 KCNJ4_HUMAN (1-445): 0: 690: 100.00		DLG2_HUMAN (31-417): 8.33e-45: 170: 16.20
+	Hs
		1054723 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG2_HUMAN (31-417): 8.33e-45: 170: 16.20
+	Hs
		158266 KCNJ4_HUMAN (1-445): 0: 690: 100.00		LIN7A_HUMAN (83-172): 5.01e-29: 116: 38.89
+	Hs
		816154 KCNJ4_HUMAN (1-445): 0: 690: 100.00		LIN7C_HUMAN (83-172): 1.22e-29: 116: 40.00
+	Hs
		816152 KCNJ4_HUMAN (1-445): 0: 690: 100.00		LIN7B_HUMAN (85-172): 7.84e-29: 114: 40.91
+	Hs
		816147 KCNJ4_HUMAN (1-445): 0: 690: 100.00		DLG1_HUMAN (1-320): 1.18e-24: 110: 15.34
+	Mm
		852403 KCNJ4_MOUSE (1-445): 0: 691: 96.86		DLG4_MOUSE (44-364): 9.35e-24: 107: 16.91
+	Hs
		816146 KCNJ4_HUMAN (1-445): 0: 690: 100.00		DLG4_HUMAN (44-364): 8.62e-24: 107: 16.91
+	Hs
		1054728 KCJ12_HUMAN (7-445): 0: 660: 63.86		LIN7C_HUMAN (83-172): 1.22e-29: 116: 40.00
+	Hs
		158284 KCJ12_HUMAN (7-445): 0: 660: 63.86		LIN7A_HUMAN (83-172): 5.01e-29: 116: 38.89
+	Hs
		1054726 KCJ12_HUMAN (7-445): 0: 660: 63.86		LIN7B_HUMAN (85-172): 7.84e-29: 114: 40.91
+	Hs
		1021490 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG1_HUMAN (1-320): 1.18e-24: 110: 15.34
+	Hs
		942342 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG4_HUMAN (44-364): 8.62e-24: 107: 16.91
+	Hs
		1054724 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG3_HUMAN (17-345): 3.57e-23: 105: 16.67
+	Mm
		1143540 Q9QYK8_MOUSE (9-439): 0: 657: 97.45		DLG4_MOUSE (44-364): 9.35e-24: 107: 16.91
+	Hs
		80982 KCJ18_HUMAN (7-445): 0: 654: 63.41		DLG1_HUMAN (1-320): 1.18e-24: 110: 15.34
+	Rn
		677769 KCJ12_RAT (7-445): 0: 648: 63.55		DLG4_RAT (44-364): 7.6e-24: 107: 16.91