HitPredict

Interactor 1: PI42A (P48426)
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha) (Diphosphoinositide kinase 2-alpha) (PIP5KIII) (Phosphatidylinositol 5-Phosphate 4-Kinase) (PI5P4Kalpha) (Phosphatidylinositol 5-phosphate 4-kinase type II alpha) (PI(5)P 4-kinase type II alpha) (PIP4KII-alpha) (PtdIns(4)P-5-kinase B isoform) (PtdIns(4)P-5-kinase C isoform) (PtdIns(5)P-4-kinase isoform 2-alpha)
Gene: PIP4K2A

Interactor 2: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	32707033, 36736316
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 391
+	Hs
		817710 PI42A_HUMAN (1-406): 4.07e-180: 508: 100.00		CSK23_HUMAN (1-391): 5.89e-133: 388: 98.47
+	Hs
		934085 PI42B_HUMAN (11-406): 3.27e-166: 474: 78.30		CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00
+	Hs
		942424 PI42B_HUMAN (11-406): 3.27e-166: 474: 78.30		CSK23_HUMAN (1-391): 5.89e-133: 388: 98.47
+	Hs
		586616 PI42A_HUMAN (1-406): 4.07e-180: 508: 100.00		CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08
+	Hs
		934336 PI42C_HUMAN (16-405): 1.05e-161: 462: 65.33		CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00
+	Hs
		1243535 PI42C_HUMAN (16-405): 1.05e-161: 462: 65.33		CSK23_HUMAN (1-391): 5.89e-133: 388: 98.47
+	Hs
		586679 PI42B_HUMAN (11-406): 3.27e-166: 474: 78.30		CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08
+	Hs
		586875 PI42C_HUMAN (16-405): 1.05e-161: 462: 65.33		CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08