HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: IF4A1 (P60842)
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1)
Gene: EIF4A1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	21280222, 34732716
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 406
+	Hs
		571352 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		DDX5_HUMAN (10-406): 3.38e-138: 409: 29.88
+	Hs
		818320 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		DDX17_HUMAN (2-406): 1.31e-136: 409: 29.33
+	Mm
		818707 SOX2_MOUSE (1-317): 8.01e-72: 226: 94.67		DDX17_MOUSE (2-406): 1.38e-137: 409: 29.33
+	Mm
		818738 SOX2_MOUSE (1-317): 8.01e-72: 226: 94.67		Q8BTS0_MOUSE (10-406): 4.82e-138: 409: 29.88
+	Hs
		757505 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		IF4A3_HUMAN (1-406): 1.93e-134: 393: 66.75
+	Hs
		1271630 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		DDX17_HUMAN (2-406): 1.31e-136: 409: 29.33
+	Hs
		571557 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		DDX5_HUMAN (10-406): 3.38e-138: 409: 29.88
+	Hs
		571415 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		DDX5_HUMAN (10-406): 3.38e-138: 409: 29.88
+	Hs
		996809 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		DDX17_HUMAN (2-406): 1.31e-136: 409: 29.33
+	Hs
		757585 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		IF4A3_HUMAN (1-406): 1.93e-134: 393: 66.75
+	Hs
		892878 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		IF4A1_HUMAN (1-406): 1.84e-132: 387: 100.00