HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: MDEAS (Q6PJG2)
Mitotic deacetylase-associated SANT domain protein (ELM2 and SANT domain-containing protein 1)
Gene: MIDEAS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	28794006, 35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 1045
+	Hs
		818811 SOX9_HUMAN (28-260): 2.6e-37: 140: 27.57		MDEAS_HUMAN (1-1045): 2.44e-153: 484: 100.00
+	Hs
		818368 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		TREF1_HUMAN (99-1045): 6.17e-87: 306: 25.05
+	Hs
		818412 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		MTA3_HUMAN (685-1043): 4.18e-89: 299: 14.18
+	Mm
		818740 SOX2_MOUSE (1-317): 8.01e-72: 226: 94.67		TREF1_MOUSE (99-1045): 1.62e-87: 308: 24.87
+	Hs
		818012 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		MTA1_HUMAN (682-1043): 1.69e-74: 262: 13.92
+	Hs
		818240 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		MIER1_HUMAN (660-1038): 3.46e-75: 259: 17.96
+	Hs
		295961 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		MTA2_HUMAN (682-1043): 2.3e-72: 255: 14.32
+	Mm
		1142022 Q60I23_MOUSE (1-317): 7.89e-75: 234: 96.24		MTA2_MOUSE (682-1043): 5.29e-74: 260: 14.58
+	Mm
		101824 Q60I23_MOUSE (1-317): 7.89e-75: 234: 96.24		F8WHY8_MOUSE (682-1043): 4.63e-72: 255: 14.43
+	Hs
		727796 SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27		MTA3_HUMAN (685-1043): 4.18e-89: 299: 14.18
+	Hs
		818591 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		RCOR1_HUMAN (723-1035): 2.65e-56: 205: 15.67
+	Hs
		1312025 HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32		MTA3_HUMAN (685-1043): 4.18e-89: 299: 14.18
+	Hs
		818553 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		RCOR3_HUMAN (723-1035): 5.14e-51: 190: 16.31
+	Hs
		1229952 HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32		MIER1_HUMAN (660-1038): 3.46e-75: 259: 17.96
+	Hs
		296145 HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32		MTA2_HUMAN (682-1043): 2.3e-72: 255: 14.32
+	Mm
		818741 SOX2_MOUSE (1-317): 8.01e-72: 226: 94.67		RCOR2_MOUSE (703-1035): 2.64e-40: 158: 16.91
+	Hs
		727824 SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27		RCOR1_HUMAN (723-1035): 2.65e-56: 205: 15.67
+	Hs
		727817 SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27		RCOR3_HUMAN (723-1035): 5.14e-51: 190: 16.31
+	Hs
		1223944 HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32		RCOR2_HUMAN (703-1016): 7.23e-58: 210: 17.93
+	Hs
		1342341 HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32		RCOR3_HUMAN (723-1035): 5.14e-51: 190: 16.31