HitPredict

Interactor 1: PP1B (P48462)
Serine/threonine-protein phosphatase beta isoform (EC 3.1.3.16) (Protein flap wing)
Gene: flw

Interactor 2: Q7K9H6 (Q7K9H6)
Zinc finger FYVE domain-containing protein
Gene: Sara

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.627

Property	Details
Experiments	12134149, 17007873
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0046872 - metal ion binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 330 Dm			1 1343
+	Dm
		819288 PP1B_DROME (1-330): 0: 592: 100.00		Q960V6_DROME (1-1343): 0: 1300: 99.93
+	Dm
		819213 PP11_DROME (1-330): 0: 563: 81.21		Q7K9H6_DROME (1-1343): 0: 1304: 100.00
+	Dm
		524621 PP12_DROME (1-303): 0: 548: 85.48		Q7K9H6_DROME (1-1343): 0: 1304: 100.00
+	Dm
		524637 PP12_DROME (1-303): 0: 548: 85.48		Q960V6_DROME (1-1343): 0: 1300: 99.93
+	Dm
		984178 PP13_DROME (6-303): 0: 542: 85.57		Q7K9H6_DROME (1-1343): 0: 1304: 100.00
+	Dm
		984188 PP13_DROME (6-303): 0: 542: 85.57		Q960V6_DROME (1-1343): 0: 1300: 99.93
+	Hs
		313521 PP1B_HUMAN (1-329): 0: 581: 88.75		ZFYV9_HUMAN (82-1341): 0: 1020: 29.52
+	Hs
		313511 PP1G_HUMAN (1-330): 0: 572: 82.48		ZFYV9_HUMAN (82-1341): 0: 1020: 29.52
+	Hs
		313520 PP1A_HUMAN (1-326): 0: 570: 82.73		ZFYV9_HUMAN (82-1341): 0: 1020: 29.52
+	Hs
		906513 PP1B_HUMAN (1-329): 0: 581: 88.75		ZFY16_HUMAN (12-1341): 0: 1005: 26.35
+	Hs
		737894 PP1G_HUMAN (1-330): 0: 572: 82.48		ZFY16_HUMAN (12-1341): 0: 1005: 26.35
+	Hs
		905987 PP1A_HUMAN (1-326): 0: 570: 82.73		ZFY16_HUMAN (12-1341): 0: 1005: 26.35
+	Hs
		906509 PP1B_HUMAN (1-329): 0: 581: 88.75		FGD5_HUMAN (81-697): 2.43e-58: 223: 14.76
+	Hs
		905981 PP1A_HUMAN (1-326): 0: 570: 82.73		FGD5_HUMAN (81-697): 2.43e-58: 223: 14.76
+	Hs
		905891 PP1A_HUMAN (1-326): 0: 570: 82.73		DCTN1_HUMAN (17-440): 5.48e-44: 177: 10.27
+	Hs
		915216 PP2AB_HUMAN (3-303): 1.07e-177: 495: 46.36		CE350_HUMAN (46-836): 2.4e-52: 205: 10.90
+	Hs
		930885 PP2AA_HUMAN (4-303): 3.18e-177: 494: 46.18		CE350_HUMAN (46-836): 2.4e-52: 205: 10.90