HitPredict

Interactor 1: RAC2 (P48554)
Ras-related protein Rac2
Gene: RAC2

Interactor 2: SYDE (Q9V9S7)
Rho GTPase-activating protein 100F (RhoGAP-100F) (Synapse defective protein 1 homolog) (Protein syd-1 homolog)
Gene: RhoGAP100F

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29217522
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras, Ras~RhoGAP
Common GO terms	GO:0007266 - Rho protein signal transduction GO:0042995 - cell projection
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Dm			1 1866
+	Hs
		253311 RHOQ_HUMAN (4-179): 1.12e-84: 250: 66.48		SRGP2_HUMAN (761-1566): 1.67e-94: 334: 14.50
+	Hs
		253337 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		SRGP2_HUMAN (761-1566): 1.67e-94: 334: 14.50
+	Hs
		564582 RHOQ_HUMAN (4-179): 1.12e-84: 250: 66.48		SYDE1_HUMAN (747-1197): 2.93e-96: 330: 33.41
+	Hs
		200213 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		SRGP3_HUMAN (749-1533): 1.15e-92: 329: 15.01
+	Mm
		925798 RAC1_MOUSE (1-192): 5.39e-84: 248: 89.58		BCR_MOUSE (786-1154): 1.9e-86: 312: 29.15
+	Hs
		506566 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		BCR_HUMAN (786-1154): 2.6e-84: 306: 28.64
+	Hs
		302639 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		FA13A_HUMAN (921-1637): 2.59e-84: 302: 15.54
+	Hs
		64652 RHOQ_HUMAN (4-179): 1.12e-84: 250: 66.48		RHG32_HUMAN (894-1785): 1.58e-80: 298: 16.22
+	Hs
		64688 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		RHG32_HUMAN (894-1785): 1.58e-80: 298: 16.22
+	Mm
		925803 RAC1_MOUSE (1-192): 5.39e-84: 248: 89.58		RHG32_MOUSE (894-1830): 1.34e-76: 285: 14.54
+	Hs
		564503 RHOQ_HUMAN (4-179): 1.12e-84: 250: 66.48		RHG05_HUMAN (620-1168): 3.49e-76: 282: 15.02
+	Hs
		63073 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		RHG42_HUMAN (767-1427): 1.34e-75: 273: 14.67
+	Hs
		147862 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		RHG33_HUMAN (851-1826): 1.96e-73: 272: 14.60
+	Mm
		925793 RAC1_MOUSE (1-192): 5.39e-84: 248: 89.58		ABR_MOUSE (646-1162): 1.84e-75: 272: 22.67
+	Hs
		551044 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		CHIN_HUMAN (943-1142): 5.04e-65: 230: 30.00
+	Mm
		925802 RAC1_MOUSE (1-192): 5.39e-84: 248: 89.58		CHIO_MOUSE (943-1142): 2.11e-66: 230: 29.00
+	Hs
		564492 RHOQ_HUMAN (4-179): 1.12e-84: 250: 66.48		RHG01_HUMAN (909-1148): 1.78e-59: 214: 25.10
+	Mm
		925805 RAC1_MOUSE (1-192): 5.39e-84: 248: 89.58		RHG22_MOUSE (864-1202): 1.82e-57: 215: 23.12
+	Mm
		925791 RAC1_MOUSE (1-192): 5.39e-84: 248: 89.58		RHG01_MOUSE (909-1150): 2.53e-59: 213: 24.90
+	Hs
		564562 RHOQ_HUMAN (4-179): 1.12e-84: 250: 66.48		RHG21_HUMAN (195-928): 3.23e-10: 67.6: 11.32