HitPredict

Interactor 1: TRF5 (P48561)
Poly(A) RNA polymerase protein 1 (EC 2.7.7.19) (Topoisomerase 1-related protein TRF5)
Gene: TRF5

Interactor 2: PAP2 (P53632)
Poly(A) RNA polymerase protein 2 (EC 2.7.7.19) (DNA polymerase kappa) (DNA polymerase sigma) (Topoisomerase 1-related protein TRF4)
Gene: PAP2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.829

The method score is based on:

Property Details
Experiments 15935758, 12665575, 37968396
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains NTP_transf_2~NTP_transf_2, NTP_transf_2~PAP_assoc
Common GO terms GO:0000292 - RNA fragment catabolic process
GO:0003729 - mRNA binding
GO:0005730 - nucleolus
GO:0031123 - RNA 3'-end processing
GO:0031499 - TRAMP complex
and 12 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 642
Sc

1 584
+ Sp
+ At
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024