HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 541 Hs			1 768
+	Hs
		826653 TCPG_HUMAN (14-540): 0: 572: 33.15		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042381 TCPH_HUMAN (12-539): 0: 570: 29.64		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		573253 TCPA_HUMAN (26-541): 0: 545: 32.08		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		821203 TCPE_HUMAN (1-541): 0: 635: 100.00		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		843193 TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Sp
		251317 TCPG_SCHPO (12-539): 0: 562: 34.21		CUL3_SCHPO (11-768): 0: 648: 37.04
+	Hs
		843192 TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Sp
		843529 TCPD_SCHPO (32-533): 1.49e-98: 310: 37.45		CUL3_SCHPO (11-768): 0: 648: 37.04
+	Hs
		843318 TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80		CUL5_HUMAN (25-768): 0: 597: 23.77