HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: DCAF5 (Q96JK2)
DDB1- and CUL4-associated factor 5 (Breakpoint cluster region protein 2) (BCRP2) (WD repeat-containing protein 22)
Gene: DCAF5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 942
+	Hs
		826824 TCPG_HUMAN (14-540): 0: 572: 33.15		DCAF5_HUMAN (1-942): 0: 784: 99.15
+	Hs
		821253 TCPE_HUMAN (1-541): 0: 635: 100.00		DCAF8_HUMAN (3-381): 2.27e-82: 279: 20.75
+	Hs
		473605 TCPH_HUMAN (12-539): 0: 570: 29.64		DC8L2_HUMAN (3-388): 7.67e-86: 290: 21.13
+	Hs
		826701 TCPG_HUMAN (14-540): 0: 572: 33.15		DCAF8_HUMAN (3-381): 2.27e-82: 279: 20.75
+	Hs
		821392 TCPE_HUMAN (1-541): 0: 635: 100.00		KTNB1_HUMAN (5-215): 3.31e-52: 196: 20.66
+	Hs
		826807 TCPG_HUMAN (14-540): 0: 572: 33.15		FBXW7_HUMAN (1-303): 8.46e-68: 242: 17.38
+	Hs
		821326 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1B_HUMAN (221-662): 4.18e-45: 171: 13.44
+	Hs
		826784 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1B_HUMAN (221-662): 4.18e-45: 171: 13.44
+	Hs
		821355 TCPE_HUMAN (1-541): 0: 635: 100.00		SNR40_HUMAN (325-549): 8.04e-24: 106: 11.61
+	Hs
		821316 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1A_HUMAN (329-653): 4.87e-23: 104: 13.14
+	Hs
		821437 TCPE_HUMAN (1-541): 0: 635: 100.00		NLE1_HUMAN (305-552): 2.5e-21: 100: 14.39
+	Hs
		821313 TCPE_HUMAN (1-541): 0: 635: 100.00		WDTC1_HUMAN (46-218): 5.91e-14: 78.2: 32.04
+	Hs
		792942 TCPG_HUMAN (14-540): 0: 572: 33.15		LIS1_HUMAN (266-571): 7.71e-32: 131: 11.04
+	Hs
		821152 TCPE_HUMAN (1-541): 0: 635: 100.00		WDR5_HUMAN (1-84): 3.55e-11: 67.6: 15.12
+	Hs
		826772 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1A_HUMAN (329-653): 4.87e-23: 104: 13.14
+	Ce
		812723 TCPE_CAEEL (3-540): 0: 586: 68.40		LIN53_CAEEL (94-224): 3.91e-10: 65.1: 30.00
+	Hs
		826764 TCPG_HUMAN (14-540): 0: 572: 33.15		WDTC1_HUMAN (46-218): 5.91e-14: 78.2: 32.04
+	Hs
		826748 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5B_HUMAN (1-81): 5.81e-12: 69.9: 15.66
+	Hs
		826601 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5_HUMAN (1-84): 3.55e-11: 67.6: 15.12
+	Hs
		903467 TCPH_HUMAN (12-539): 0: 570: 29.64		WDR5_HUMAN (1-84): 3.55e-11: 67.6: 15.12