HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.947

The method score is based on:

Property Details
Experiments 24981860, 33961781, 35271311, 35235311, 37071682, 28514442
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cpn60_TCP1~Cpn60_TCP1
Common GO terms GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005832 - chaperonin-containing T-complex
GO:0005874 - microtubule
GO:0006457 - protein folding
and 13 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 541
Hs

1 543
+ Bt
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Bt
+ Sc
+ Ph
+ Sc
+ Bt
+ Hs
+ Hs
+ Hs
+ At
+ Dm
+ Dm
+ Hs

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Last updated: 15 Jul 2024