Protein: RFA3
Replication factor A protein 3 (RF-A) (Replication protein A 13 kDa subunit)

Gene: RFA3
Organism: Saccharomyces cerevisiae S288C
Interactions: 87
UniProt ID: P26755

Gene Ontology (top 5):
GO:0000723 - telomere maintenance
GO:0000722 - telomere maintenance via recombination
GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0000794 - condensed nuclear chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

607217

RFA1
Replication factor A protein 1

18

0

Small-scale

0.935

High

644733

RFA2
Replication factor A protein 2

10

0

Small-scale

0.924

High

419602

RAD52
DNA repair and recombination protein RAD52

4

0

Small-scale

0.668

High

644797

ATR
Serine/threonine-protein kinase MEC1

4

0

Small-scale

0.667

High

644786

RFA3
Replication factor A protein 3

1

0

Small-scale

0.589

High

644800

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2 [Includes: DNA replication nuclease DNA2

2

0

High-throughput

0.576

High

644824

LCD1
DNA damage checkpoint protein LCD1

2

0

Small-scale

0.569

High

644820

MSH6
DNA mismatch repair protein MSH6

2

1

High-throughput

0.567

High

629322

MSH3
DNA mismatch repair protein MSH3

1

1

High-throughput

0.536

High

644804

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.504

High

575887

ADT3
ADP,ATP carrier protein 3

1

1

High-throughput

0.489

High

644803

GPP2
Glycerol-1-phosphate phosphohydrolase 2

1

1

High-throughput

0.489

High

644808

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

1

High-throughput

0.489

High

632549

RAD51
DNA repair protein RAD51

1

0

Small-scale

0.480

High

392068

H2A1
Histone H2A.1

1

1

High-throughput

0.479

High

392324

H2A2
Histone H2A.2

1

1

High-throughput

0.479

High

644795

BDF1
Bromodomain-containing factor 1

1

0

Small-scale

0.458

High

644819

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.458

High

644822

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.458

High

644823

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

644825

POB3
FACT complex subunit POB3

1

0

High-throughput

0.458

High

341950

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.457

High

389241

HXKA
Hexokinase-1

1

1

High-throughput

0.457

High

423781

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

High-throughput

0.457

High

498453

METK1
S-adenosylmethionine synthase 1

1

1

High-throughput

0.457

High

570669

HXKG
Glucokinase-1

1

1

High-throughput

0.457

High

575918

ADT2
ADP,ATP carrier protein 2

1

1

High-throughput

0.457

High

583204

METK2
S-adenosylmethionine synthase 2

1

1

High-throughput

0.457

High

644830

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

1

High-throughput

0.457

High

644831

THI21
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21

1

1

High-throughput

0.457

High

355375

H2B1
Histone H2B.1

1

1

High-throughput

0.437

High

355807

H2B2
Histone H2B.2

1

1

High-throughput

0.437

High

490503

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.407

High

493340

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.407

High

510457

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.407

High

644793

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.407

High

644802

RT105
Regulator of Ty1 transposition protein 105

3

0

Small-scale

0.352

High

644833

CMR1
DNA damage-binding protein CMR1

2

0

High-throughput

0.318

High

644816

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

2

0

High-throughput

0.310

High

644826

RNH1
Ribonuclease H

2

0

High-throughput

0.307

High

644806

MPH1
ATP-dependent DNA helicase MPH1

2

0

Small-scale

0.305

High

634910

VAC17
vacuole-related protein 17

2

0

Small-scale

0.295

High

440862

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.279

Low

644792

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.279

Low

644796

PGM2
Phosphoglucomutase 2

1

0

High-throughput

0.279

Low

644801

HXT7
High-affinity hexose transporter HXT7

1

0

High-throughput

0.279

Low

644809

MMM1
Maintenance of mitochondrial morphology protein 1

1

0

Small-scale

0.279

Low

644812

YJ9I
Uncharacterized protein YJR141W

1

0

High-throughput

0.279

Low

644815

EF3B
Elongation factor 3B

1

0

High-throughput

0.279

Low

644821

WDR59
Maintenance of telomere capping protein 5

1

0

High-throughput

0.279

Low

644827

IMB1
Importin subunit beta-1

1

0

High-throughput

0.279

Low

342350

CISY1
Citrate synthase, mitochondrial

1

0

High-throughput

0.261

Low

343550

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.261

Low

360765

TBB
Tubulin beta chain

1

0

High-throughput

0.261

Low

365894

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.261

Low

367797

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.261

Low

381432

GAL1
Galactokinase

1

0

High-throughput

0.261

Low

381689

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

0

High-throughput

0.261

Low

520929

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.261

Low

554578

HSP26
Heat shock protein 26

1

0

High-throughput

0.261

Low

560581

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.261

Low

587967

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.261

Low

644788

BMH1
Protein BMH1

1

0

High-throughput

0.261

Low

644794

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.261

Low

644799

KSP1
Serine/threonine-protein kinase KSP1

1

0

High-throughput

0.261

Low

644810

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.261

Low

356286

H4
Histone H4

1

0

High-throughput

0.249

Low

638650

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.249

Low

644787

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

644789

HS104
Heat shock protein 104

1

0

High-throughput

0.249

Low

644790

BTAF1
TATA-binding protein-associated factor MOT1

1

0

Small-scale

0.249

Low

644791

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

644798

SLI15
Inner centromere protein-related protein SLI15

1

0

Small-scale

0.249

Low

644805

VPS27
Vacuolar protein sorting-associated protein 27

1

0

High-throughput

0.249

Low

644807

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

644811

BIR1
Protein BIR1

1

0

Small-scale

0.249

Low

644813

GIS2
Zinc finger protein GIS2

1

0

High-throughput

0.249

Low

644814

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.249

Low

644817

H3
Histone H3

1

0

High-throughput

0.249

Low

644818

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.249

Low

644828

NEJ1
Non-homologous end-joining protein 1

1

0

Small-scale

0.249

Low

644829

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

644832

SMC4
Structural maintenance of chromosomes protein 4

1

0

Small-scale

0.249

Low

496025

RLA3
Large ribosomal subunit protein P1B

1

0

High-throughput

0.238

Low

519902

TCPA
T-complex protein 1 subunit alpha

1

0

High-throughput

0.232

Low

612204

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024