HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: MEP50 (Q9BQA1)
Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50)
Gene: WDR77

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 342
+	Hs
		134771 TCPE_HUMAN (1-541): 0: 635: 100.00		PEX7_HUMAN (29-334): 2.89e-68: 218: 22.54
+	Sc
		772894 TCPE_YEAST (3-540): 0: 582: 59.89		PFS2_YEAST (78-327): 8.69e-79: 250: 25.69
+	Hs
		826849 TCPG_HUMAN (14-540): 0: 572: 33.15		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		821437 TCPE_HUMAN (1-541): 0: 635: 100.00		NLE1_HUMAN (114-333): 2.06e-53: 184: 18.05
+	Hs
		792942 TCPG_HUMAN (14-540): 0: 572: 33.15		LIS1_HUMAN (62-339): 9.49e-75: 238: 16.72
+	Hs
		821326 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1B_HUMAN (163-340): 1.65e-45: 163: 21.79
+	Hs
		134772 TCPG_HUMAN (14-540): 0: 572: 33.15		PEX7_HUMAN (29-334): 2.89e-68: 218: 22.54
+	Hs
		821316 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1A_HUMAN (201-341): 1.98e-27: 112: 18.31
+	At
		138361 TCPE_ARATH (6-538): 0: 606: 68.29		PEX7_ARATH (168-333): 1.4e-34: 130: 23.81
+	Hs
		826784 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1B_HUMAN (163-340): 1.65e-45: 163: 21.79
+	Hs
		826807 TCPG_HUMAN (14-540): 0: 572: 33.15		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Sc
		744632 TCPE_YEAST (3-540): 0: 582: 59.89		TAF5_YEAST (15-267): 2.96e-38: 146: 14.77
+	Hs
		821387 TCPE_HUMAN (1-541): 0: 635: 100.00		TBL1Y_HUMAN (207-337): 6.68e-19: 89.3: 14.38
+	Hs
		821152 TCPE_HUMAN (1-541): 0: 635: 100.00		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		196971 TCPE_HUMAN (1-541): 0: 635: 100.00		PRP4_HUMAN (253-341): 3.86e-10: 62.8: 13.40
+	Hs
		826772 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1A_HUMAN (201-341): 1.98e-27: 112: 18.31
+	Hs
		826848 TCPG_HUMAN (14-540): 0: 572: 33.15		TBL1Y_HUMAN (207-337): 6.68e-19: 89.3: 14.38
+	Hs
		826601 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		196973 TCPG_HUMAN (14-540): 0: 572: 33.15		PRP4_HUMAN (253-341): 3.86e-10: 62.8: 13.40
+	Hs
		826748 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5B_HUMAN (3-106): 2.76e-09: 59.7: 7.90